Source botanique

Quercetin 3-O-gentiobioside is a flavonoid glycoside, which is a plant-derived compound known for its potential health benefits. This compound is predominantly sourced from various plant species, where it functions as part of the plant's defense mechanisms. The mode of action of Quercetin 3-O-gentiobioside primarily involves its antioxidant properties, allowing it to scavenge free radicals and reduce oxidative stress within biological systems. Due to these properties, Quercetin 3-O-gentiobioside has been studied for its potential applications in health sciences, particularly in the areas of anti-inflammatory and cardiovascular research. Its ability to modulate enzymatic activity and interact with cellular signaling pathways suggests a range of possible therapeutic uses. Current research focuses on its role in protecting cells from oxidative damage, which may contribute to its protective effects against chronic conditions. As a model compound, it also provides insight into the structure-function relationship of flavonoids and their biological activities.

(+)-Gallocatechin as a bio-antimutagenic compound against UV-induced mutation in Escherichia coli. It is potent in scavenging Fremy’s salt, a synthetic free radical, it possesses antioxidant capacities that is higher or comparable to that of ascorbic acid or Trolox.

Zingibroside R1 has anti-HIV-1 activity.

Ginsenoside Ro is a triterpenoid saponin, which is a secondary metabolite found primarily in Panax ginseng. This compound is isolated from the roots of the ginseng plant, a source well-documented for its rich array of bioactive constituents. Ginsenoside Ro functions through various biochemical pathways, including modulating inflammatory signaling cascades and exhibiting antioxidant activity. It interacts with molecular targets such as enzymes and receptors involved in the inflammatory response, thereby exerting its effects on cellular processes. Ginsenoside Ro's applications are diverse, with its primary uses in the fields of pharmacology and integrative medicine. It is investigated for its potential in managing inflammatory diseases, oxidative stress, and metabolic disorders. Understanding the precise molecular mechanisms of Ginsenoside Ro continues to be an area of active research, aiming to elucidate its full therapeutic potential and optimize its application in clinical settings. This saponin exemplifies the intricate relationship between natural products and modern medicine, providing valuable insights for developing novel therapeutic strategies.

Camelliaside B is a natural product from Camellia oleifera Abel.

Glycitein accounts for 5-10% of the total isoflavones in soy food products, has weak estrogenic activity, comparable to that of the other soy isoflavones but much lower than that of DES and 17beta-estradiol.

Timosaponin BII has anti-diabetes, antioxidant, anti-inflammatory, and anti-dementia activities, it can significantly reduce the neurotoxicity induced by beta amyloid peptide 25-35 in primary neurons, the mechanism of which may be related with resisting oxidative damage and regulating the cholinergic system.Timosaponin BII can improve the neurological symptoms of cerebral ischemic rat, reduce infarct size, relieve brain water edema, improve hemorheology, reduce inflammatory injury of cerebral ischemia; it could be used in the preparation of a medicament or product for the prevention and treatment of stroke.

Plantamajoside is a phenylethanoid glycoside isolated primarily from Plantago asiatica, which is a perennial herb known for its pharmacological benefits. This compound functions through its anti-inflammatory and antioxidant properties, effectively modulating pathways such as the NF-κB signaling and scavenging reactive oxygen species (ROS). These mechanisms contribute to its potential therapeutic effects in managing inflammation and oxidative stress-related conditions. Plantamajoside has garnered attention for its applications in the treatment of inflammatory diseases such as arthritis and dermatitis. Additionally, its antioxidative activity supports its use in combating oxidative-related cellular damage. Current research also explores its role in neuroprotection, as it may help prevent neuronal damage in neurodegenerative diseases. With growing interest in natural product-based therapies, Plantamajoside provides a promising avenue for further investigation in biomedical research.

Diosbulbin B has potential anti-tumor effects which may be related to influencing the immune system for the first time, it also exhibits potential hepatotoxicity.

Nicotiflorin is a flavonoid glycoside extracted from a traditional Chinese medicine Flos Carthami, it has a protective effect against cerebral ischemic damage.

Astragaloside II can downregulate the expression of the P-gp and mdr1 gene, suppress phosphorylation of extracellular signal regulated kinase 1/2, p38 and c-Jun N-terminal kinase, suggests that Astragaloside II is a potent multidrug resistance (MDR) reversal agent and may be a potential adjunctive agent for hepatic cancer chemotherapy.

Acteoside is a lipase inhibitor, has neuroprotective, anti-obesity,anti-inflammatory, antioxidant, anticancer, cytotoxic,antihypertensive, analgesic, and antimetastatic activities. Acteoside can promote nerve growth factor and tropomycin receptor kinase A expression, inhibit arachidonic acid release and prostaglandin E2 production induced by 0.5 microM melittin. Acteoside can protect the cells from X-ray induced damage through enhancing the scavenging activity of ROS, decreasing the Bax/Bcl-2 ratio and downregulating the activity of procaspase-3, as well as modulating the mitogen-activated protein kinase signaling pathways.

Wogonin is one major constituent of Scutellaria baicalensis, possesses potent anticancer activities , the activities are largely due to their abilities to scavenge oxidative radicals, to attenuate NF-kappaB activity, to inhibit several genes important for regulation of the cell cycle, to suppress COX-2 gene expression and to prevent viral infections.