Phytochimiques

Applications It was isolated from Garcinia mangostana Linn (Guttiferae). It is an anti-inflammatory agent. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Chairungsrilerd, N., et al.: Planta Med., 62, 471 (1996), Chen, Y., et al.: Biochem. Pharmacol., 59, 1445 (2000), Matsumoto, K., et al.: Bioorg. Med. Chem., 12, 5799 (2004), Ramprasath, V., et al.: Biol. Pharm. Bull., 27, 2028 (2004),

Stability Hygroscopic Applications Quercetin 3-Sulfate Potassium Salt is an metabolite of Quercetin (Q509500), a mitochondrial ATPase and phosphodiesterase inhibitor with potential anticancer activities. References El-Mousallami, A.M.D., et al.: Natural. Prod. Sci., 6, 193 (2000); Haraguchi, H. et al.: J. Natural. Prod., 59, 443 (1996);

Applications Phorbol is a plant-derived diterpene that exhibits various biological activities such as its role as tumor promoters through the activation of protein kinase C. References Bourjot, M., et al.: J. Nat. Prod., 75, 2183 (2012); Xiao, L., et al.: J. Biol. Chem. 284, 29365 (2009);

Stability Light Sensitive Applications Crocetin is a carotenoid derived from saffron, and is shown to have anticancer effects in both human adenocarcinoma gastric cancer cells and rat model of gastric cancer. References Bathaie, S. Z., et al.: Biochem. Cell Bio., 91, 397 (2013); Nam K. N., et al.: Euro. J. Pharmac., 648(1-3), 110 (2010);

Stability Very Hygroscopic Applications Mixed conjugate of dietary phytoestrogen. References Adlercreutz, H;., et al.: J. Steroid Mol. Biol., 52, 97 (1995), Kinjo, J., et al.: Biol. Pharm. Bull., 27, 185 (2004),

Stability Hygroscopic Applications Convicine 15N,13C is an isotope labelled form of Convicine (C685095). References Rizzello, C. G., et al.: Sci. Rep., 6, 32452 (2016); Pulkkinen, M., et al.: Food Chem., 212, 10-19 (2016); McNulty, J., et al.: Bioorg. Med. Chem. Lett., 24, 4586 (2014)

Applications Metanicotine-d3 is the isotope labelled analog of Metanicotine (M321250); an alkaloid found in the leaves of Duboisia Hopwoodii and a constitutent of tobacco smoke. Also used as a potential drug for the treatment of senile dementia of the Alzheimer’s type, and currently being investigated as a nicotinic agonist with CNS selectivity. Metanicotine may have clinical potential due to its high selectivity for CNS nicotinic acetylcholine receptor subtypes relative to peripheral ganglionic and muscle-type nicotinic acetylcholine receptors. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Schmeltz, I., et al.: J. Sci. Food Agric., 15, 744 (1964); Griffin, W.J. and Luanratana, O.: Phytochemistry, 21, 499 (1982); Jacob III, P., et al.: J. Chromatogr., 619, 49 (1993); Lippiello, P.M., et al.: J. Pharm. Exp. Therap., 279, 1422 (1996)

Applications α-Eudesmol is an isomer of β-Eudesmol (E938600), a sesquiterpenoid known to induce neurite outgrowth. β-Eudesmol exhibits antiangiogenic activity. References Obara, Y. et al.: J. Pharmacol. Exp . Ther., 30, 803 (2011); Tsuneki, H. et al.: Eur. J. Pharmacol., 512, 105 (2005);