APIs pour la recherche et les impuretés

Applications Acetaminophen Glutathione Disodium Salt is a metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3,4). References (1) Chen, C., et al.: Xenobiotica, 30, 1019 (2000) (2) Ikeda, H., et al.: Biochem. J., 364, 563 (2002) (3) Aleksunes, L., et al.: Toxicol. Sci., 83, 44 (2005) (4) Elsby, R., et al.: J. Biol. Chem., 278, 22243 (2003)

Bendamustine is a drug that belongs to the class of alkylating agents. It is used in the treatment of cancer and chronic lymphocytic leukemia. Bendamustine is a synthetic compound, which has been shown to have oncosis (cancer-causing) properties. Bendamustine can be administered intravenously as a dry powder or in tablet form and has shown efficacy against neoplastic cells. Its mechanism of action involves binding to DNA and inhibiting the synthesis of RNA and DNA, thereby interfering with cell division. The drug also binds to erythrocytes, leading to methemoglobinemia. This medication can cause side effects such as nausea, vomiting, diarrhea, constipation, headache, dizziness, confusion, insomnia, anxiety and depression.

Deschloro aripiprazole is a drug product that has been analyzed for impurities. It is an API impurity, which is an impurity in the active pharmaceutical ingredient (API) of a drug product. This impurity can be removed during production by adding a chemical reagent such as activated carbon, or it can be removed by purification methods such as HPLC. Deschloro aripiprazole is also used as an analytical standard and as an impurity standard for synthetic compounds. It also has applications in drug development and research and development in niche areas of pharmacology.

Applications (S)-10-Monohydroxy-10,11-dihydro Carbamazepine is the metabolite of Eslicarbazepine acetate, (BIA 2-093), (E659000) a novel central nervous system drug. References Duncan, J., et al.: Br. J. Clin. Pharmacol., 53, 123 (2002), Almeida, L., et al.: J. Clin. Pharmacol., 45, 1062 (2005), Coppola, G., et al.: CNS Drugs, 18, 133 (2004),

Please enquire for more information about (3,5-Dimethyl-2-hexeno)-4-hydroxyphenone including the price, delivery time and more detailed product information at the technical inquiry form on this page

Stability Hygroscopic Applications Synthetic thrombin inhibitor. Thrombin mutant anticoagulant antagonist. Antithrombotic. References Dewanjee, M., et al.: J. Nucl. Med., 22, 981 (1981), Goodman, S., et al.: J. Biomed. Mater. Res., 45, 240 (1999), Carlsson, S., et al.: Thromb. Res., 115, 9 (2005),

Fluorometholone impurity 5 is a drug product that has been custom synthesized. It has not yet been assigned to a CAS number. This compound exhibits high purity and is an analytical grade. Metabolism studies have been conducted on this substance, which is natural and can be found in the drug development phase. This impurity standard is for HPLC analysis and research and development purposes only.

Thymol iodide is a compound of Iodide and Thymol. It is mostly used as mild antiseptic and fungicide.

Risperidone carboxylate impurity is an analytical reference standard of risperidone that is used in the research and development, drug development, and production of drugs. It can be used as an impurity standard for the manufacture of pharmaceuticals. Risperidone carboxylate impurity has a molecular weight of 514.83 g/mol and a melting point of 200-202°C. Its CAS number is 1346603-86-8. Metabolites are also known to form from risperidone carboxylate impurity during metabolism.

Applications Nilotinib-d6, is the labeled analogue of Nilotinib (N465300), which might be useful in treatment of chronic myelogenous leukemia. It is a COVID19-related research product. References Corbin, A., et al.: J. Biol. Chem., 277, 32214(2002), Golemovic, M., et al.: Clin. Cancer Res., 11, 4941 (2005), Gleixner, K., et al.: Blood, 107, 752 (2006), Nicolini, F., et al.: Leukemia, 20, 1061 (2006),

2-[(Tetrahydropyran-2-yl)oxy]ethyl p-toluenesulfonate is a drug product. The compound is an impurity in the API, which is a metabolite of the synthetic chemical 2-[(Tetrahydropyran-2-yl)oxy]ethyl p-toluenesulfonate (CAS No. 65338-95-6). This impurity has been identified by HPLC analysis and was found to have natural origin. It has been detected in various batches of the API, although at different concentrations. It may also be present as an analytical or impurity standard for HPLC analysis.