APIs pour la recherche et les impuretés

Meclofenamate sodium hydrate is a non-steroidal anti-inflammatory drug that inhibits cyclooxygenase, lipoxygenase, and phospholipase A 2 . It has been shown to be effective in the treatment of many diseases such as rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, and gout. Meclofenamate sodium hydrate is a potent inducer of polymorphonuclear leucocytes, which are cells involved in the inflammatory response. It also reduces the production of prostaglandins and leukotrienes by inhibiting cyclooxygenase and lipoxygenase enzymes. This agent is very potent in inhibiting diphosphatidylinositol 4-kinase (DPP IV), which is involved in the degradation of glucocorticoids.

Applications A metabolite of Midazolam (M343000). References Soucek, P., et al.: Xenobiotica, 22, 83 (1992), Ghosal, A., et al.: Drug Metab. Dispos., 24, 940 (1996), Kobayashi, K., et al.: Biochem. Pharmacol., 63, 889 (2002),

Please enquire for more information about Bensulide including the price, delivery time and more detailed product information at the technical inquiry form on this page

Isotopically labelled metabolite of telmisartan

Everolimus related compound 3 is a chemical compound that contains xylose, chamomile extract, cellulose, sulfadiazine, and other ingredients. It is commonly used in industrial applications and has various properties and uses. This compound has been found to have interactions with glutamate, basic proteins, tocopherol, biomass, ticagrelor, chemokines, P. aeruginosa, and other substances. It may also contain impurities such as growth factors and fatty acids. Its specific applications and benefits will depend on the intended use in different industries.

Please enquire for more information about Clofedanol o-β-D-glucuronide including the price, delivery time and more detailed product information at the technical inquiry form on this page

Stability Light Sensitive Applications The isotopically labelled drug Sulfadiazine. Antibacterial. References Bohni, et al.: Chemotherapy, 14, 195 (1969), Carr, et al.: Antimicrob. Agents Chemother., 4, 585 (1973), Stober, H., et al.: Anal. Profiles Drug Subs., 11, 523 (1982),

Applications Third generation platinum complex. An antitumor agent with activity against colorectal cancer. Cytotoxicity follows the formation of adducts with DNA. Antineoplastic. References Kidani, Y., et al.: J. Med. Chem., 21, 1315 (1978), Kizu, R., et al.: Cancer Chemother. Pharmacol., 31, 475 (1993), Levi, F., et al.: Eur. J. Cancer, 29A, 1280 (1993), Simpson, D., et al.: Drugs, 63, 2127 (2003),

Applications An amine reactive trifunctional cross linker.

Triphenylmethanol (TPM) is an inhibitor of the enzyme alcohol dehydrogenase. It is synthesized by reacting p-hydroxybenzoic acid with a hydroxyl group in the presence of trifluoroacetic acid and potassium carbonate. The reaction solution was then analyzed by x-ray crystallography, revealing the molecular structure of TPM. TPM binds to the metal ion in a hydroxyl group, preventing alcohol dehydrogenase from oxidizing ethanol to acetaldehyde. This mechanism also explains why TPM inhibits other enzymes that use this same metal ion cofactor such as carboxypeptidase A and aminopeptidase P, which are involved in protein synthesis and degradation. Triphenylmethanol (TPM) is an inhibitor of the enzyme alcohol dehydrogenase. It is synthesized by reacting p-hydroxybenzoic acid with a hydroxyl group in the presence of trif