APIs pour la recherche et les impuretés

(2S,2R,Cis)-saxagliptin is a drug product that has been developed for the treatment of type II diabetes. It is an orally active DPP-4 inhibitor that inhibits the degradation of GLP-1 and GIP and lowers blood glucose levels in patients with type II diabetes mellitus. It binds to the serine/threonine protein phosphatase catalytic site of DPP-4. (2S,2R,Cis)-saxagliptin can be used as a standard for HPLC analysis and as a research and development compound in the study of its metabolism. This drug product is not on the World Health Organization's list of essential medicines. (2S,2R,Cis)-saxagliptin is also not on the United States Pharmacopeia’s list of approved drugs.

Applications Avibactam (NXL104) is a novel β-lactamase inhibitor with a non-lactam structural scaffold. NXL104 irreversibly inhibits lactamase from Mycobacterium tuberculosis. References Iland, C., et al.: J. Pathol. Bacteriol., 58, 495 (1946), Flores, A., et al.: Microbiology, 151, 521 (2005), Livermore, D., et al.: J. Antimicrob. Chemother., 62, 1053 (2008), Tremblay, L., et al.: Biochemistry, 49, 9685 (2010),

Please enquire for more information about FASN-IN-1 including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications FOY 251-D4 is a labelled analogue of FOY 251 (F754500).

Applications Analgesic. References Simonsen, K., et al.: J. Anal. Toxicol., 34, 367 (2010), Komsta, L., et al.: J. Pharm. Biomed. Anal., 53, 911 (2010),

1-beta-D-Ribofuranosyl-3-guanylurea picrate is also known as 1-(diaminomethylene)-3-(beta-D-ribofuranosyl)urea picrate, 1-amidino-3-b-D-ribofuranosylurea monopicrate and Azacitidine Related Compound C. 1-beta-D-Ribofuranosyl-3-guanylurea picrate is an impurity generated from the hydrolysis of the drug Azacitidine, available on the market with the trade name Vidaza. Azacitidine is a chemical analogue of cytidine and is used in the treatment of myelodysplastic syndrome.