Modulateurs d'enzymes
Les modulateurs d'enzymes sont des composés qui peuvent augmenter ou inhiber l'activité des enzymes, régulant ainsi la vitesse des réactions biochimiques. Ces modulateurs jouent un rôle essentiel dans le contrôle des voies métaboliques, de la signalisation cellulaire et de divers processus physiologiques. Les modulateurs d'enzymes sont largement utilisés dans la recherche et le développement de médicaments pour étudier les fonctions enzymatiques et développer des agents thérapeutiques. Chez CymitQuimica, nous proposons une gamme complète de modulateurs d'enzymes de haute qualité pour soutenir vos recherches sur la régulation enzymatique et la découverte de médicaments.
Sous-catégories appartenant à la catégorie "Modulateurs d'enzymes"
Produits appartenant à la catégorie "Modulateurs d'enzymes"
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Saracatinib
CAS :Inhibitor of Src and Abl tyrosine kinases; anti-proliferative; anti-migratoryFormule :C27H32ClN5O5Degré de pureté :Min. 95%Masse moléculaire :542.03 g/molSB 239063 - Bio-X ™
CAS :This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.Formule :C20H21FN4O2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :368.4 g/molVolitinib
CAS :Inhibitor of c-Met kinaseFormule :C17H15N9Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :345.36 g/molEN 6
CAS :Autophagy activator that acts through targeting the ATP6V1A subunit of vATPaseFormule :C19H14F2N4O2Degré de pureté :Min. 95%Couleur et forme :White To Yellow To Beige SolidMasse moléculaire :368.34 g/molN-[3-(1,3-Benzodioxol-5-yl)pyrazolo[1,5-a]pyrimidin-5-yl]-N',N'-dimethyl-propane-1,3-diamine
Selective inhibitor of the mutated RET variant RETV804M, which is the anticipated drug-resistant RET mutant that can occur in tumours treated with kinase inhibitors. The compound has a biochemical IC50 of 0.02 µM and selectivity for purified RETV804M over purified RET and KDR of 3.7 and 110, respectively. The efficacy of the compound was shown also in cell cultures with IC50 of 4.4 µM, and cell assay selectivity for RETV804M over RET and KDR of 0.89 and 2.3, respectively.Formule :C18H21N5O2Degré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :339.39 g/molrac-Perhexiline maleate
CAS :Inhibitor of CPT1 and CPT2 enzymes; inhibitor of mTORC1 kinase; anti-fungalFormule :C23H39NO4Degré de pureté :Min. 97 Area-%Couleur et forme :White To Off-White SolidMasse moléculaire :393.56 g/molTandutinib
CAS :Tyrosine kinase inhibitor; antineoplastic activity; pro-apoptoticFormule :C31H42N6O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :562.7 g/molAmlexanox - Bio-X ™
CAS :Amlexanox is an antiallergic and anti-inflammatory drug that has been shown to be effective in treating rhinitis and allergic asthma in clinical studies. It prevents the slow-reacting substance of anaphylaxis (SRS-A) from being released chemically as a mediator and may have antagonistic effects on interleukin-3. Amlexanox is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.Formule :C16H14N2O4Degré de pureté :(%) Min. 99%Couleur et forme :PowderMasse moléculaire :298.29 g/molAZ 960
CAS :ATP competitive JAK2 inhibitorFormule :C18H16F2N6Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :354.36 g/molGDC 0941
CAS :Pan-class I phosphatidylinositide 3-kinase (PI3K) inhibitor (IC50 = 3, 33, 3 and 75 nM at catalytic subunits p110α, p110β, p110δ and p110γ respectively). Inhibits proliferation in several cancer cell lines, such as glioblastoma, breast and prostate cancer cells. Has synergistic anti-cancer effect in combination with MEK/ERK kinase inhibitor GDC-0973 (cobimetinib).Formule :C23H27N7O3S2Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :513.64 g/molNilotinib - Bio-X ™
CAS :Nilotinib is tyrosine kinase inhibitor drug that is used to treat chronic myeloid leukemia (CML). It inhibits the activity of the BCR-ABL protein kinase, which is involved in the development of CML. Additionally, it inhibits PDGF and c-kit for the potential treatment of various leukemias. Nilotinib is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.Formule :C28H22F3N7ODegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :529.52 g/molDutasteride - Bio-X ™
CAS :Dutasteride is an androgenic compound and a 5α-reductase inhibitor that is used to treat benign prostatic hyperplasia (BPH) and male pattern baldness. Dutasteride reduces prostate volume and improves symptoms of BPH by inhibiting the enzyme 5α-reductase, which converts testosterone to dihydrotestosterone. Dutasteride is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.Formule :C27H30F6N2O2Degré de pureté :(%) Min. 99%Couleur et forme :PowderMasse moléculaire :528.53 g/mol4-Deoxyuridine
CAS :A cytidine analogue and inhibitor of DNA methyl transferases (DNMTs) with anti-cancer activity. This stable, hydrophilic compound forms covalent complexes between DNMT and zebularine-substrate DNA. It causes DNA lesions that block replication and cause replication fork collapse, leading to the formation of DNA double-strand breaks. It was also shown that zebularine-induced DNA methylation decrease in the IL-1β promoter region and disrupts molecular mechanisms of neuroinflammation. Moreover, this molecule down-regulates the DNA-methylation profile in the pluripotency genes’ promoters, which leads to improved development of somatic cell nuclear transfer (SCNT) embryos.Formule :C9H12N2O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :228.21 g/molCarfilzomib
CAS :Inhibits proteosomes of class peptide epoxyketone; antineoplasticFormule :C40H57N5O7Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :719.91 g/molT 3364366
CAS :A potent, reversible and slow-binding inhibitor of delta-5 desaturases (D5Ds), by binding to the desaturase domain. Inhibiting D5D has therapeutic applications in inflammatory diseases. This is due to the increase in anti-inflammatory DGLA-derived eicosanoids and decrease in pro-inflammatory AA-derived eicosanoids.Formule :C18H16F3N3O3S2Degré de pureté :Min. 95%Couleur et forme :SolidMasse moléculaire :443.47 g/molZaprinast
CAS :Phosphodiesterase (PDE5, 6, 9 and 11) inhibitorFormule :C13H13N5O2Degré de pureté :Min. 95%Couleur et forme :Pink To Light (Or Pale) Tan SolidMasse moléculaire :271.27 g/molArgatroban monohydrate
CAS :A reversible and selective inhibitor of thrombin that rapidly binds to the catalytic site directly. Inhibits both soluble and bound forms of thrombin. Used for prophylaxis and treatment of heparin-induced thrombocytopenia type II.Formule :C23H36N6O5S•H2ODegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :526.65 g/molPF 9366
CAS :An allosteric inhibitor of human methionine adenosyltransferase 2A (Mat2A), the extrahepatic isoform, with an IC50 value of 420nM. Binding of PF9366 to Mat2A overlaps with the binding site of Mat2B, a regulator of Mat2A. Mat2A inhibition in cells by PF 9366 reduces synthesis of S-adenosylmethionine (SAM).Formule :C20H19ClN4Degré de pureté :Min. 95%Couleur et forme :SolidMasse moléculaire :350.84 g/molGSK 126
CAS :GSK-126 is a potent inhibitor of histone lysine methyl transferase 2, which is encoded by the enhancer of zeste homolog 2 gene (EZH2). The EZH2 protein regulates cell cycle as it represses the Polycomb-Repressive Complex 2 (PRC2), allowing cells to divide actively. GSK-126 inhibits the EZH2 by targeting the catalytic domain (SET) of the enzyme and therefore blocks the PCR2 repression mechanism, resulting in cell proliferation arrest. The compound has shown therapeutic potential for a variety of cancers.Formule :C31H38N6O2Degré de pureté :Min. 95%Couleur et forme :White To Yellow SolidMasse moléculaire :526.30562Irsogladine maleate - Bio-X ™
CAS :Irsogladine is a gastroprotective drug that is used for the treatment of GERD and gastric ulcers. This drug also has antioxidant properties. Irsogladine is a phosphodiesterase-4 inhibitor and increases levels of cAMP. It helps to prevent and heal damage to the stomach lining. Irsogladine maleate is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.Formule :C13H11Cl2N5O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :372.16 g/mol
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