CAS: 1036016-10-0

Levofloxacin hydroxy acid is a high purity, drug product with a HPLC standard. It is used for drug development and research. Levofloxacin hydroxy acid has been developed as an analytical reference standard for the detection of impurities in API manufacturing. The pharmacopoeia includes levofloxacin hydroxy acid as an impurity standard. Levofloxacin hydroxy acid is also used in metabolism studies to investigate the role of levofloxacin's active metabolite, M-2, on the activity of CYP2C8 and CYP3A4 enzymes.

Applications Levofloxacin Hydroxy Acid is found in the synthesis of Levofloxacin (L360000), S-(-)-form of Ofloxacin. An antibiotic used against gram-negative organisms. References Kato, M., et al.: Arzneim.-Forsch., 42, 365 (1992), North, D.S., et al.: Pharmacotherapy, 18, 915 (1998), Hwang, D.G., et al.: Br. J. Ophthalmol., 87, 1004 (2003),