CAS: 1061214-06-9

4-[2-[1-(4-Methylphenyl)ethylidene]hydrazinyl]benzenesulfonamide is an organic compound that is used as a clinical medication. It is a pyrazole derivative that has been shown to be effective as an oxidizing agent for the synthesis of sulfonyl chlorides. 4-[2-[1-(4-Methylphenyl)ethylidene]hydrazinyl]benzenesulfonamide reacts with thionyl chloride in the presence of a base such as pyridine to form 2-chloro-N,N'-dihydroxyethane sulfonic acid, which can be converted into other sulfonyl chlorides. This reaction requires a long reaction time and should be conducted in an inert solvent such as dichloromethane or chloroform. The structure of 4-[2-[1-(4-methylphenyl)ethylidene]hydrazinyl]benzenesulfon

Applications 4-[2-[1-(4-Methylphenyl)ethylidene]hydrazinyl]benzenesulfonamide is an impurity of Celecoxib (C251000), a selective cyclooxygenase-2 (COX-2) inhibitor. Anti-inflammatory. Used in treatment of familial adenomatous polyposis. Celecoxib is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing hormones that cause inflammation and pain in the body. References Simon, L.S., et al.: Arthritis Rheum., 41, 1591 (1998), Silverstein, F.E., et al.: J. Am. Med. Assoc., 284, 1247 (2000), Steinbach, G., et al.: N. Engl. J. Med., 342, 1946 (2000),

4-(2-(1-(p-Tolyl)ethylidene)hydrazinyl)benzenesulfonamide is a useful organic compound for research related to life sciences. The catalog number is T64550 and the CAS number is 1061214-06-9.