CAS 107007-99-8: Cloridrato di Granisetron
Descrizione:
Cloridrato di Granisetron è un antagonista selettivo del recettore della serotonina 5-HT3 utilizzato principalmente come antiemetico per prevenire nausea e vomito associati a chemioterapia, radioterapia e chirurgia. È una polvere cristallina bianca o bianco sporco solubile in acqua e presenta un intervallo di pH tipicamente compreso tra 4 e 6 quando disciolto. La formula molecolare di Cloridrato di Granisetron riflette la sua struttura, che include un anello di piperidina, contribuendo alla sua attività farmacologica. Questo composto viene spesso somministrato per via orale o endovenosa, a seconda dello scenario clinico. Il granisetron agisce bloccando l'azione della serotonina sui recettori 5-HT3 nel tratto gastrointestinale e nel sistema nervoso centrale, inibendo così il riflesso del vomito. La sua farmacocinetica indica una emivita relativamente lunga, consentendo una gestione efficace della nausea e del vomito con meno dosi. Come con qualsiasi farmaco, gli effetti collaterali potenziali possono includere mal di testa, costipazione e vertigini, richiedendo un attento monitoraggio durante il trattamento.
Formula:C18H24N4O·ClH
InChI:InChI=1/C18H24N4O.ClH/c1-21-13-6-5-7-14(21)11-12(10-13)19-18(23)17-15-8-3-4-9-16(15)22(2)20-17;/h3-4,8-9,12-14H,5-7,10-11H2,1-2H3,(H,19,23);1H/t12-,13+,14-;
InChI key:InChIKey=QYZRTBKYBJRGJB-WQTKJZBYNA-N
SMILES:C(N[C@H]1C[C@@]2(N(C)[C@](C1)(CCC2)[H])[H])(=O)C=3C=4C(N(C)N3)=CC=CC4.Cl
Sinonimi:- 1-Methyl-N-(9-Methyl-9-Azabicyclo(3.3.1)Non-3-Yl)-1H-Indazole-3-Carboxamid
- 1-Methyl-N-(9-Methyl-9-Azabicyclo[3.3.1]Non-3-Yl)-1H-Indazole-3-Carboxamide
- 1-Methyl-N-(9-Methyl-9-Azabicyclo[3.3.1]Non-3-Yl)-1H-Indazole-3-Carboxamide Hydrochloride (1:1)
- 1-Methyl-N-[(3-Endo)-9-Methyl-9-Azabicyclo[3.3.1]Non-3-Yl]-1H-Indazole-3-Carboxamide
- 1-Methyl-N-[(3-Endo)-9-Methyl-9-Azabicyclo[3.3.1]Non-3-Yl]-1H-Indazole-3-Carboxamide Hydrochloride
- 1H-Indazole-3-Carboxamide, 1-Methyl-N-(9-Methyl-9-Azabicyclo[3.3.1]Non-3-Yl)-, Monohydrochloride, Endo-
- 1H-Indazole-3-Carboxamide, 1-Methyl-N-[(3-Endo)-9-Methyl-9-Azabicyclo[3.3.1]Non-3-Yl]-, Monohydrochloride
- 1H-Indazole-3-carboxamide, 1-methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-, hydrochloride (1:1)
- 9-Azabicyclo[3.3.1]nonane, 1H-indazole-3-carboxamide deriv.
- Brl-43694A
- Brl-43694A, Kytril, 1-Methyl-N-[(3-Endo)-9-Methyl-9-Azabicyclo[3.3.1]Non-3-Yl]-1H-Indazole-3-Carboxamide Hydrochloride
- Vedi altri sinonimi
Ordinare per
12 prodotti.
Granisetron hydrochloride CRS
CAS:Granisetron hydrochloride CRSFormula:C18H25ClN4OColore e forma:White. Powder.Peso molecolare:348.8703Granisetron Hydrochloride
CAS:Prodotto controllatoApplications A specific serotonin (5HT3) receptor antagonist. Used as an antiemetic. Granisetron HCl is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy. Its main effect is to reduce the activity of the vagus nerve. It does not have much effect on vomiting due to motion sickness. This drug does not have any effect on dopamine receptors or muscarinic receptor References Kilpatrick, G.J., et al.: Nature, 330, 746 (1987), Durig, T., et al.: J. Pharm. Sci., 86, 1092 (1997), Yuasa, H., et al.: Chem. Pharm. Bull., 44, 1361 (1996),Formula:C18H24N4O·ClHColore e forma:NeatPeso molecolare:348.87Ref: ST-EA-CP-G16011
10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaGranisetron hydrochloride
CAS:Prodotto controllatoSerotonin receptor 5-HT3 antagonistFormula:C18H25ClN4OPurezza:Min. 95%Colore e forma:PowderGranisetron hydrochloride
CAS:Formula:C18H24N4O·HClPurezza:98.0 - 102.0 % (dried substance)Colore e forma:White or almost white powderPeso molecolare:348.87Granisetron Hydrochloride
CAS:Formula:C18H24N4O·HClPurezza:>98.0%(T)(HPLC)Colore e forma:White to Almost white powder to crystalPeso molecolare:348.88Granisetron HCl
CAS:Formula:C18H24N4O·HClColore e forma:White To Off-White SolidPeso molecolare:312.42 36.46Ref: 4Z-G-073
5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaGranisetron hydrochloride, 98%
CAS:This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Formula:C18H25ClN4OPurezza:98%Colore e forma:White to almost white, PowderPeso molecolare:348.88Granisetron Hydrochloride
CAS:Compounds containing an unfused pyridine ring in the structure, nesoiFormula:C18H24N4O·HClColore e forma:White Off-White PowderPeso molecolare:348.17169Granisetron hydrochloride
CAS:Granisetron hydrochloride (Granisetron HCl) is a serotonin receptor (5HT-3 selective) antagonist that has been used as an antiemetic for cancer chemotherapyFormula:C18H25ClN4OPurezza:99.88% - 99.93%Colore e forma:White To Off-White Crystalline SolidPeso molecolare:348.87
