CAS 1115-70-4: Cloridrato di metformina
Descrizione:
Cloridrato di metformina è un agente ipoglicemizzante orale utilizzato principalmente nella gestione del diabete mellito di tipo 2. Appartiene alla classe dei farmaci biguanidi e funziona diminuendo la produzione epatica di glucosio, migliorando la sensibilità all'insulina e migliorando l'assorbimento e l'utilizzo periferico del glucosio. La sostanza appare come una polvere cristallina bianca o bianco sporco, solubile in acqua ma con solubilità limitata nei solventi organici. La sua formula chimica è C4H11N5·HCl e ha un peso molecolare di circa 165,63 g/mol. Cloridrato di metformina è tipicamente somministrato in forma di compressa ed è noto per il suo profilo di sicurezza favorevole, con effetti collaterali gastrointestinali che sono i più comuni. È anche associato a un basso rischio di ipoglicemia quando usato da solo. Inoltre, la ricerca ha indicato potenziali benefici oltre al controllo glicemico, inclusa la protezione cardiovascolare e la gestione del peso. Come per qualsiasi farmaco, è essenziale utilizzare metformina sotto supervisione medica, considerando controindicazioni e potenziali interazioni con altri farmaci.
Formula:C4H11N5·ClH
InChI:InChI=1S/C4H11N5.ClH/c1-9(2)4(7)8-3(5)6;/h1-2H3,(H5,5,6,7,8);1H
InChI key:InChIKey=OETHQSJEHLVLGH-UHFFFAOYSA-N
SMILES:C(NC(=N)N)(N(C)C)=N.Cl
Sinonimi:- 1,1-Dimethylbiguanide Hydrochloride
- 3-(Diaminomethylidene)-1,1-Dimethylguanidine Hydrochloride (1:1)
- Apo-Metformin
- Apophage
- Benofomin
- Biguanide, 1,1-dimethyl-, hydrochloride
- Biguanide, 1,1-dimethyl-, monohydrochloride
- Dabex
- Denkaform
- Dextin
- Diabefagos
- Vedi altri sinonimi
Ordinare per
METFORMIN HYDROCHLORIDE CRS
CAS:METFORMIN HYDROCHLORIDE CRSFormula:C4H12ClN5Colore e forma:PowderPeso molecolare:165.6246Metformin hydrochloride
CAS:Metformin hydrochloride (1,1-Dimethylbiguanide hydrochloride) is an AMPK activator. Metformin is used in type 2 diabetes research. Cost-effective and quality-assured.Formula:C4H12ClN5Purezza:97.53% - 99.00%Colore e forma:White Or Almost White Crystals Solid CrystallinePeso molecolare:165.63Metformin hydrochloride, EP grade
CAS:Formula:C4H11N5·HClPurezza:98.5 - 101.0 % (dried substance)Colore e forma:White or almost white crystalsPeso molecolare:165.62N1,N1-Dimethylbiguanide hydrochloride
CAS:Purezza:95.0%Colore e forma:SolidPeso molecolare:165.63000488281251,1-Dimethylbiguanide hydrochloride, 97%
CAS:This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Formula:C4H12ClN5Purezza:97%Colore e forma:Crystalline powder, WhitePeso molecolare:165.63Metformin HCl - Bio-X ™
CAS:Metformin is a widely used anti-hyperglycemic (anti-diabetic) agent for the treatment of type 2 diabetes mellitus. This is due to it decreasing blood glucose by decreasing hepatic glucose product by activation of the AMP-activated protein kinase AMPK. Studies have also demonstrated Metformin to have anti-cancer activity, attributed to several mechanisms such as inhibition of mammalian target of rapamycin (mTOR), cancer stem cells and inflammation. Metformin HCl is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready to use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.Formula:C4H11N5•HClPurezza:Min. 95%Colore e forma:PowderPeso molecolare:165.62 g/mol1,1-Dimethylbiguanide hydrochloride
CAS:1,1-Dimethylbiguanide hydrochloride is used as an antidiabetic agent, used in polycystic ovary syndrome, non-alcoholic fatty liver disease and diabetes mellitus type 2. It may also reduce weight gain in people taking atypical antipsychotics, used in a study to investigate its role in enhancing the secretions of plasma active glucagon-like peptide-1 (GLP-1) levels. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Formula:C4H12ClN5Colore e forma:White, Crystalline powderPeso molecolare:165.63Metformin Hydrochloride
CAS:Formula:C4H11N5·HClPurezza:>98.0%(T)(HPLC)Colore e forma:White to Almost white powder to crystalPeso molecolare:165.63Metformin Hydrochloride
CAS:Prodotto controllatoApplications An oral hypoglycemic agent. Slows electron transport in the oxidation pathway in mitochondria. Has been reported to reverse Lupus symptoms in mice in conjunction with 2-deoxy-d-glucose (D239000). Metformin is a well-known type 2 diabetes treatment. Research shows that metformin may inhibit tumor growth both directly and indirectly. Studies indicate that metformin modulates the biology of aging. Metformin blocks the conversion of select substrates into glucose in a redox-dependent manner. References Tucker, G.T., et al.: Brit. J. Clin. Pharmacol., 12, 235 (1981), DeFronzo, R.A., et al.: N. Engl. J. Med., 333, 541 (1995); Chem. and Eng. News, page 7, Feb. 23 (2015); Nir Barzilai et al., Cell Metabolism 23: 1060 June 14 (2016); Chem. and Eng. News, page 7, Feb. 23 (2015); Chem. and Eng. News, page 12, July 30 (2018)Formula:C4H11N5·ClHColore e forma:WhitePeso molecolare:165.62Ref: ST-EA-CP-M3008
10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaMetformin hydrochloride
CAS:Metformin hydrochlorideFormula:C4H12N5ClPurezza:100%Colore e forma:WhitePeso molecolare:165.62571,1-Dimethylbiguanide hydrochloride
CAS:1,1-Dimethylbiguanide hydrochlorideFormula:C4H11N5·ClHPurezza:96% (Typical Value in Batch COA)Colore e forma: white solidPeso molecolare:165.62g/molMetformin HCl
CAS:Metformin is a widely used anti-hyperglycemic (anti-diabetic) agent for the treatment of type 2 diabetes mellitus. This is due to it decreasing blood glucose by decreasing hepatic glucose product by activation of the AMP-activated protein kinase AMPK. Studies have also demonstrated Metformin to have anti-cancer activity, attributed to several mechanisms such as inhibition of mammalian target of rapamycin (mTOR), cancer stem cells and inflammation.Formula:C4H12ClN5Colore e forma:White PowderPeso molecolare:165.62 g/molMetformin hydrochloride
CAS:Formula:C4H11N5·HClPurezza:(Titration) 98.0 - 102.0 % (dried basis)Colore e forma:White or almost white crystalline powderPeso molecolare:165.62Metformin hydrochloride (mM/ml)
CAS:Formula:C4H12ClN5Purezza:98%Colore e forma:SolidPeso molecolare:165.6246
