CAS 114-49-8: Bromidrato di scopolamina
Descrizione:
Bromidrato di scopolamina è un alcaloide tropano derivato da piante della famiglia Solanaceae, in particolare dalla pianta della belladonna. È una polvere cristallina bianca o bianco sporco che è solubile in acqua e alcol, rendendola adatta per varie formulazioni farmaceutiche. La sostanza agisce principalmente come un agente anticolinergico, bloccando l'azione dell'acetilcolina nel sistema nervoso, il che la rende efficace nel trattamento della cinetosi, nausea e vomito. Bromidrato di scopolamina è anche utilizzato in contesti preoperatori per ridurre la salivazione e le secrezioni. I suoi effetti farmacologici includono sedazione, amnesia e rilassamento muscolare, ma può anche causare effetti collaterali come secchezza delle fauci, visione offuscata e sonnolenza. A causa del suo potenziale di abuso e del rischio di effetti collaterali gravi, il suo uso è attentamente monitorato in contesti clinici. Come per qualsiasi farmaco, è essenziale utilizzare Bromidrato di scopolamina sotto la guida di un professionista sanitario per garantire sicurezza ed efficacia.
Formula:C17H21NO4·BrH
InChI:InChI=1S/C17H21NO4.BrH/c1-18-13-7-11(8-14(18)16-15(13)22-16)21-17(20)12(9-19)10-5-3-2-4-6-10;/h2-6,11-16,19H,7-9H2,1H3;1H/t11-,12-,13-,14+,15-,16+;/m1./s1
InChI key:InChIKey=WTGQALLALWYDJH-MOUKNHLCSA-N
SMILES:CN1[C@@]2([C@]3([C@](O3)([C@]1(C[C@@H](OC([C@H](CO)C4=CC=CC=C4)=O)C2)[H])[H])[H])[H].Br
Sinonimi:- (-)-Scopolamine bromide
- (-)-Scopolamine, HBr
- (1S,2R,4S,5S)-9-methyl-3-oxa-9-azatricyclo[3.3.1.0~2,4~]non-7-yl 3-hydroxy-2-phenylpropanoate hydrobromide (1:1)
- 1α<span class="text-smallcaps">H</smallcap>,5α<smallcap>H</span>-Tropan-3α-ol, 6β,7β-epoxy-, (-)-tropate (ester), hydrobromide
- 3-Oxa-9-azatricyclo[3.3.1.0<sup>2,4</sup>]nonane, benzeneacetic acid deriv.
- 9-Methyl-3-Oxa-9-Azatricyclo[3.3.1.0~2,4~]Non-7-Yl 3-Hydroxy-2-Phenylpropanoate Hydrobromide (1:1)
- 9-Methyl-3-Oxa-9-Azatricyclo[3.3.1.0~2,4~]Non-7-Yl 3-Hydroxy-2-Phenylpropanoate Hydrochloride
- Beldavrin
- Benzeneacetic acid, α-(hydroxymethyl)-, (1α,2β,4β,5α,7β)-9-methyl-3-oxa-9-azatricyclo[3.3.1.0<sup>2,4</sup>]non-7-yl ester, hydrobromide (1:1), (αS)-
- Benzeneacetic acid, α-(hydroxymethyl)-, (1α,2β,4β,5α,7β)-9-methyl-3-oxa-9-azatricyclo[3.3.1.0<sup>2,4</sup>]non-7-yl ester, hydrobromide, (αS)-
- Benzeneacetic acid, α-(hydroxymethyl)-, 9-methyl-3-oxa-9-azatricyclo[3.3.1.0<sup>2,4</sup>]non-7-yl ester, hydrobromide, [7(S)-(1α,2β,4β,5α,7β)]-
- Vedi altri sinonimi
Ordinare per
8 prodotti.
Scopolamine HBr (Hyoscine HBr)
CAS:Formula:C17H21NO4·HBrColore e forma:White To Off-White SolidPeso molecolare:303.36 80.91Ref: 4Z-S-012
5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaScopolamine-13C, D3 Hydrobromide
CAS:Prodotto controllatoApplications Scopolamine-13C, d3 Hydrobromide, is the labeled analogue of Scopolamine-d3 Hydrobromide (S200002), an acetylcholine antagonist, used in treatment of motion sickness; antiemetic; antispasmodic; mydriatic; preanesthetic medicant. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Brand, J.J., et al.: Lancet, 2, 232 (1970), Bowles, J.B., et al.: Anaesthesia, 34, 476 (1979), Clissold, S.P., et al.: Drugs, 29, 189 (1985), Muhtadi, F.J., et al.: Anal. Profiles Drug Subs., 19, 477 (1990),Formula:C1613CH19D3BrNO4Colore e forma:Off-WhitePeso molecolare:388.28Scopolamine Hydrobromide Trihydrate
CAS:Formula:C17H21NO4·HBr·3H2OPurezza:>98.0%(T)(HPLC)Colore e forma:White to Almost white powder to crystalPeso molecolare:438.32Scopolamine Hydrobromide Hydrate
CAS:Prodotto controllatoApplications Scopolamine Hydrobromide Hydrate is an acetylcholine antagonist. Used in treatment of motion sickness; antiemetic; antispasmodic; mydriatic; preanesthetic medicant. Neuroprotective & Neuroresearch Product. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Brand, J.J., et al.: Lancet, 2, 232 (1970); Bowles, J.B., et al.: Anaesthesia, 34, 476 (1979); Clissold, S.P., et al.: Drugs, 29, 189 (1985); Muhtadi, F.J., et al.: Anal. Profiles Drug Subs., 19, 477 (1990);Formula:C17H21NO4·HBr·xH2OColore e forma:White SolidPeso molecolare:384.26(1S,2R)-9-Methyl-3-oxa-9- azatricyclo[3.3.1.02,4]nonan-7-yl (2S)-3-hydroxy-2-phenylpropanoate trihydrate hydrobromide
CAS:(1S,2R)-9-Methyl-3-oxa-9- azatricyclo[3.3.1.02,4]nonan-7-yl (2S)-3-hydroxy-2-phenylpropanoate trihydrate hydrobromidePeso molecolare:438.31g/molScopolamine hydrobromide
CAS:Scopolamine hydrobromide is an anticholinergic medication, which is a derivative of tropane alkaloids sourced primarily from Solanaceae family plants, such as Hyoscyamus niger and Datura stramonium. Its mode of action involves competitive inhibition of acetylcholine at muscarinic receptors in the central and peripheral nervous systems. This blocking effect impedes parasympathetic nerve impulses, leading to diminished activity in smooth muscles and glandular secretions. This compound is extensively used in clinical settings for the prevention and treatment of motion sickness and postoperative nausea and vomiting. Its ability to cross the blood-brain barrier makes it effective in influencing central nervous system activities, particularly within the vestibular pathways. Additionally, it has applications in ophthalmology for pupil dilation due to its mydriatic effect. The understanding of its molecular interactions and effects on neurotransmitter pathways is crucial for advancing therapeutic uses, as well as minimizing potential side effects such as dry mouth and blurred vision.Formula:C17H21NO4·HBrPurezza:Min. 95%Colore e forma:PowderPeso molecolare:384.26 g/molScopolamine hydrobromide
CAS:Natural alkaloidFormula:C17H21NO4HBrPurezza:≥ 95.0 % (HPLC)Colore e forma:PowderPeso molecolare:384.27
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