CAS: 118081-37-1

Ceftibuten Hydrate is a third-generation cephalosporin antibiotic, which is a synthetic derivative of naturally occurring cephalosporin C, derived from the fungus Acremonium. It functions by inhibiting bacterial cell wall synthesis, leading to cell lysis and death. This bactericidal action is accomplished through the binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, disrupting the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls. Ceftibuten Hydrate is primarily used in the treatment of a wide range of infections caused by susceptible strains of bacteria, including respiratory tract infections, otitis media, and urinary tract infections. Its oral administration offers a convenient treatment option, particularly for outpatient settings. The compound is effective against both gram-positive and gram-negative bacteria, making it a versatile choice in combating bacterial resistance. Due to its pharmacokinetics and safety profile, Ceftibuten Hydrate is a valuable therapeutic tool in clinical settings, contributing significantly to the management of infectious diseases.