CAS 120210-48-2: Tenidap
Descrizione:
Tenidap è un composto chimico che appartiene alla classe dei farmaci anti-infiammatori non steroidei (FANS). È principalmente riconosciuto per le sue potenziali proprietà anti-infiammatorie e analgesiche, rendendolo rilevante nel trattamento di condizioni come l'artrite. Il composto agisce inibendo specifici enzimi coinvolti nel processo infiammatorio, riducendo così dolore e gonfiore. Tenidap è caratterizzato dalla sua unica struttura molecolare, che include gruppi funzionali che contribuiscono alla sua attività biologica. Viene tipicamente somministrato per via orale ed è stato studiato per la sua farmacocinetica, inclusi assorbimento, distribuzione, metabolismo ed escrezione. Sebbene abbia mostrato promesse in contesti clinici, l'uso di Tenidap può essere associato a effetti collaterali comuni ai FANS, come disagio gastrointestinale o rischi cardiovascolari. Come per qualsiasi agente farmaceutico, il suo uso terapeutico dovrebbe essere guidato da un professionista sanitario, considerando il profilo di salute specifico del paziente e le potenziali interazioni farmacologiche.
Formula:C14H9ClN2O3S
InChI:InChI=1S/C14H9ClN2O3S/c15-7-3-4-9-8(6-7)11(13(19)17(9)14(16)20)12(18)10-2-1-5-21-10/h1-6,18H,(H2,16,20)/b12-11-
InChI key:InChIKey=LXIKEPCNDFVJKC-QXMHVHEDSA-N
SMILES:C(\O)(=C\1/C=2C(N(C(N)=O)C1=O)=CC=C(Cl)C2)/C3=CC=CS3
Sinonimi:- (3Z)-5-Chloro-2,3-dihydro-3-(hydroxy-2-thienylmethylene)-2-oxo-1H-indole-1-carboxamide
- (Z)-5-Chloro-3-(alpha-hydroxy-2-thenylidene)-2-oxo-1-indolinecarboxamide
- 1H-Indole-1-carboxamide, 5-chloro-2,3-dihydro-3-(hydroxy-2-thienylmethylene)-2-oxo-, (3Z)-
- 1H-Indole-1-carboxamide, 5-chloro-2,3-dihydro-3-(hydroxy-2-thienylmethylene)-2-oxo-, (Z)-
- 5-chloro-2-hydroxy-3-(thiophen-2-ylcarbonyl)-1H-indole-1-carboxamide
- 5-chloro-2-oxo-3-(thiophen-2-ylcarbonyl)-2,3-dihydro-1H-indole-1-carboxamide
- Cp 66,248
- Tenidap [USAN:INN:BAN]
- Tenidapum
- Tenidapum [INN-Latin]
- Unii-9K7Cj74Onh
- Vedi altri sinonimi
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6 prodotti.
Tenidap
CAS:Prodotto controllatoApplications Tenidap is one of the nonsteroidal antiinflammatory drugs (NSAIDs). Tenidap is an NSAID that preferentially inhibits COX-1. Tenidap inhibits formation of pro-inflammatory arachidonic acid metabolites in isolated human peripheral polymorphonuclear leukocytes. References Moilanen, et al.: Eicosanoids, 1, 35 (1988), Kirchner, et al.: J. Pharmacol. Exp. Ther., 282, 1094 (1997), Liu, et al.: Eur. J. Pharmacol., 435, 153 (2002),Formula:C14H9ClN2O3SColore e forma:NeatPeso molecolare:320.75Tenidap
CAS:Tenidap (CP-66248) is a selective COX-1 and SLC26A3 inhibitor with anti-inflammatory, analgesic, and anti-rheumatic activities.Formula:C14H9ClN2O3SPurezza:98.36% - 99.42%Colore e forma:SolidPeso molecolare:320.75Tenidap
CAS:Tenidap is a synthetic anti-inflammatory drug, which is derived from the chemical modification of nonsteroidal anti-inflammatory drugs (NSAIDs). It functions as both a cyclooxygenase (COX) inhibitor and a modulator of cytokine production. This dual mode of action allows Tenidap to simultaneously reduce the synthesis of prostaglandins by inhibiting COX enzymes and suppress the production of pro-inflammatory cytokines like interleukin-1 and tumor necrosis factor. This makes it unique compared to traditional NSAIDs. Tenidap is primarily used in the treatment of inflammatory diseases such as rheumatoid arthritis and osteoarthritis. Its efficacy in reducing joint inflammation and alleviating pain while potentially mitigating the gastrointestinal side effects associated with standard NSAIDs has been a significant area of interest. Clinical investigations have focused on its dual-action mechanism to comprehend its therapeutic benefits and safety profile, emphasizing its potential in managing chronic inflammatory conditions where both pain suppression and cytokine modulation are critical.Formula:C14H9ClN2O3SPurezza:Min. 95%Peso molecolare:320.75 g/mol
