CAS 124584-08-3: Peptide natriuretico cerebrale-32 (umano)
Descrizione:
Il peptide natriuretico cerebrale (BNP) è una neuroormone prodotto principalmente nei ventricoli cardiaci in risposta all'espansione del volume ventricolare e al sovraccarico di pressione. La forma specifica nota come peptide natriuretico cerebrale-32 (umano) è un peptide di 32 aminoacidi che svolge un ruolo cruciale nell'omeostasi cardiovascolare. Funziona promuovendo la natriuresi, la diuresi e la vasodilatazione, aiutando così a regolare la pressione sanguigna e l'equilibrio dei fluidi. Il BNP è coinvolto nella fisiopatologia dell'insufficienza cardiaca e i suoi livelli nel sangue possono servire come biomarker per diagnosticare e gestire questa condizione. Il numero CAS 124584-08-3 identifica questo peptide specifico, caratterizzato dalla sua dimensione relativamente piccola e dalla sequenza specifica di aminoacidi che lo distingue da altri peptidi natriuretici. La sua attività biologica è mediata attraverso il legame a recettori specifici, portando a vari effetti fisiologici, inclusa l'inibizione del sistema renina-angiotensina-aldosterone. In generale, il BNP è significativo sia in contesti clinici che di ricerca, in particolare in cardiologia.
Formula:C143H244N50O42S4
Sinonimi:- Natriureticfactor-32 (human brain clone lhBNP57)
- 1,2-Dithia-5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50-hexadecaazacyclotripentacontane,cyclic peptide deriv.
- 1: PN:US6028055 SEQID: 1 claimed protein
- 6: PN:US20090011997 SEQID: 4 claimed protein
- 83: PN: US20080153747 SEQID: 83 claimedprotein
- Human brain natriuretic factor-32
- Human brain natriuretic peptide-32
- L-Histidine,L-seryl-L-prolyl-L-lysyl-L-methionyl-L-valyl-L-glutaminylglycyl-L-serylglycyl-L-cysteinyl-L-phenylalanylglycyl-L-arginyl-L-lysyl-L-methionyl-L-a-aspartyl-L-arginyl-L-isoleucyl-L-seryl-L-seryl-L-seryl-L-serylglycyl-L-leucylglycyl-L-cysteinyl-L-lysyl-L-valyl-L-leucyl-L-arginyl-L-arginyl-,cyclic (10?
- 26)-Disulfide
- Natriureticpeptide type-B
- Nesiritide
- Vedi altri sinonimi
Ordinare per
10 prodotti.
BNP-32 (human) hydrochloride
CAS:BNP-32 is a peptide hormone that regulates the volume of blood in the heart and lungs. It is used to diagnose congestive heart failure, and also as a treatment for decompensated congestive heart failure. When given as an intravenous infusion, BNP-32 reduces the levels of natriuretic peptides in the blood stream by increasing their breakdown in the kidneys. The disulfide bond between cysteine residues (Cys-Cys) is essential for its activity. BNP-32 has been shown to be effective against infectious diseases such as HIV, hepatitis C, and tuberculosis. It is also used in combination with other drugs to treat high blood pressure. This drug can be administered orally or intravenously and is biocompatible with human tissue because it is chemically stable and non-toxic at therapeutic doses.Formula:C143H244N50O42S4Purezza:Min. 95%Peso molecolare:3,464.04 g/molNesiritide
CAS:Nesiritide, recombinant human B-type natriuretic peptide, binds NPR-A/C with Kd 7.3/13 pM.Formula:C143H244N50O42S4Purezza:98%Colore e forma:SolidPeso molecolare:3464.04BNP-32 (Human)
CAS:Please enquire for more information about BNP-32 (Human) including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C143H244N50O42S4Purezza:Min. 95%Peso molecolare:3,464.05 g/molBNP-32 (human)
CAS:The secretion of the cardiac hormone BNP-32 is increased considerably in patients with congestive heart failure, successful medical treatment of this condition will result in a decrease. Yandle et al. described a method for determining hBNP in human plasma. Effects of hBNP infusion in humans have been described by Holmes et al and La Villa et al. BNP is an important biomarker in the diagnosis of heart diseases. Additionally, BNP-32 may act as a neuropeptide. BNP-32 exerts strong lipolytic effects in humans.Formula:C143H244N50O42S4Purezza:97.8%Peso molecolare:3464.09BNP-32 (human)
CAS:The secretion of the cardiac hormone BNP-32 is increased considerably in patients with congestive heart failure, successful medical treatment of this condition will result in a decrease. Yandle et al. described a method for determining hBNP in human plasma. Effects of hBNP infusion in humans have been described by Holmes et al and La Villa et al. BNP is an important biomarker in the diagnosis of heart diseases. Additionally, BNP-32 may act as a neuropeptide. BNP-32 exerts strong lipolytic effects in humans.Formula:C143H244N50O42S4Purezza:97.2%Colore e forma:WhitePeso molecolare:3464.09BNP-32 human
CAS:This 32 amino acid peptide contains a 17 amino acid ring structure that is common to all natriuretic peptides. It is also called the brain natriuretic peptide (BNP) because it was first identified in porcine brain- however, the main source of this peptide is not the brain but the cardiac ventricle. This cardiac neurohormone is secreted from the ventricles in response to volume expansion and pressure overload. It has natriuretic and vasodilatory effects and suppresses the renin-angiotensin-aldosterone system.Formula:C143H244N50O42S4Colore e forma:PowderPeso molecolare:3,463.8 g/molNesiritide acetate
CAS:Nesiritide acetate is a man-made form of the natriuretic peptide hormone that is secreted by the heart. It is used to treat high blood pressure and congestive heart failure. Nesiritide acetate increases the amount of sodium and water excreted from the body, which reduces blood volume and lowers blood pressure. It also relaxes blood vessels, leading to lower blood pressure. This drug can also be used in diagnosis to assess levels of natriuretic peptides in the bloodstream. The typical therapeutic dose for this drug is 100 mcg/kg given intravenously over 30 minutes and then infusion at 0.01 mcg/kg/min for up to 24 hours. The dosage may be increased or decreased depending on the severity of symptoms or side effects experienced by the patient.Formula:C143H244N50O42S4•(C2H4O2)xPurezza:Min. 95 Area-%Colore e forma:PowderPeso molecolare:3,464.05 g/molBNP-32 (human)
CAS:Natriuretic; vasodilatory;diuretic; treats decompensated congestive hear failureFormula:C143H244N50O42S4Purezza:Min. 95%Colore e forma:PowderPeso molecolare:3,464.04 g/molBNP-32 (human)
CAS:Bachem ID: 4095916.Formula:C143H244N50O42S4Purezza:97.9%Colore e forma:WhitePeso molecolare:3464.09
