CAS: 125404-04-8

Applications TCN 238 allosteric modulator of the mGlu4 receptor (1). TCN 238 may be useful in the treatment of motor dysfunction and in the treatment of Parkinson’s disease. TCN 238 is orally bioavailable. References (1) East, S.P. et al.: Bioorg. Med. Chem. Lett., 20, 4901 (2010)

TCN238 is an orally bioavailable positive allosteric modulator of the metabotropic glutamate receptor 4 (mGluR4with an EC50 of 1 μM).

Allosteric modulator of metabotropic glutamate receptor (mGluR4)

TCN238