CAS 136656-07-0: Timosaponina B II
Descrizione:
Timosaponina B II è un composto saponinico derivato principalmente dalla specie vegetale Timosaponin, noto per le sue varie attività biologiche. È caratterizzato dalla sua complessa struttura glicosidica, che tipicamente include un aglicone steroideo o triterpenoide legato a uno o più moieties di zucchero. Questa configurazione strutturale contribuisce alle sue proprietà tensioattive, permettendogli di interagire con le membrane biologiche. Timosaponina B II è stato studiato per i suoi potenziali effetti farmacologici, comprese le attività anti-infiammatorie, anti-cancro e immunomodulatorie. Inoltre, potrebbe mostrare effetti citotossici contro alcune linee cellulari tumorali, rendendolo un argomento di interesse nella chimica medicinale. Il composto è solubile in solventi organici e potrebbe avere una solubilità limitata in acqua, comune a molte saponine. Il suo profilo di sicurezza e le potenziali applicazioni terapeutiche continuano a essere esplorati nella ricerca scientifica, evidenziando l'importanza dei prodotti naturali nella scoperta e nello sviluppo di farmaci.
Formula:C45H76O19
InChI:InChI=1S/C45H76O19/c1-19(18-58-40-37(55)34(52)31(49)27(15-46)60-40)7-12-45(57)20(2)30-26(64-45)14-25-23-6-5-21-13-22(8-10-43(21,3)24(23)9-11-44(25,30)4)59-42-39(36(54)33(51)29(17-48)62-42)63-41-38(56)35(53)32(50)28(16-47)61-41/h19-42,46-57H,5-18H2,1-4H3/t19-,20-,21+,22-,23+,24-,25-,26-,27+,28+,29+,30-,31+,32+,33-,34-,35-,36-,37+,38+,39+,40+,41-,42+,43-,44-,45+/m0/s1
InChI key:InChIKey=SORUXVRKWOHYEO-UJDJZYEZSA-N
SMILES:C[C@@]12[C@]([C@]3([C@](CC1)([C@]4(C)[C@](CC3)(C[C@@H](O[C@H]5[C@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)[C@@H](O)[C@@H](O)[C@@H](CO)O5)CC4)[H])[H])[H])(C[C@]7([C@@]2([C@H](C)[C@](CC[C@@H](CO[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)C)(O)O7)[H])[H])[H]
Sinonimi:- (3β,5β,22α,25S)-26-(β-<span class="text-smallcaps">D</smallcap>-Glucopyranosyloxy)-22-hydroxyfurostan-3-yl 2-O-β-<smallcap>D</smallcap>-glucopyranosyl-β-<smallcap>D</span>-galactopyranoside
- 1H-Naphth[2′,1′:4,5]indeno[2,1-b]furan, β-<span class="text-smallcaps">D</span>-galactopyranoside deriv.
- 25S-Timosaponin B II
- Furostan, β-<span class="text-smallcaps">D</span>-galactopyranoside deriv.
- Prototimosaponin A III
- Timosaponin B2
- Timosaponin Bii
- β-<span class="text-smallcaps">D</smallcap>-Galactopyranoside, (3β,5β,22α,25S)-26-(β-<smallcap>D</smallcap>-glucopyranosyloxy)-22-hydroxyfurostan-3-yl 2-O-β-<smallcap>D</span>-glucopyranosyl-
- 1H-Naphth[2′,1′:4,5]indeno[2,1-b]furan, β-D-galactopyranoside deriv.
- (3β,5β,22α,25S)-26-(β-D-Glucopyranosyloxy)-22-hydroxyfurostan-3-yl 2-O-β-D-glucopyranosyl-β-D-galactopyranoside
- β-D-Galactopyranoside, (3β,5β,22α,25S)-26-(β-D-glucopyranosyloxy)-22-hydroxyfurostan-3-yl 2-O-β-D-glucopyranosyl-
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7 prodotti.
Timosaponin B II
CAS:Timosaponin B II is a natural compound that inhibits the activity of cytochrome P450 enzymes. It has been shown to induce autophagy in a dopamine-dependent manner, which may be due to its ability to decrease mitochondrial membrane potential and increase phase transition temperature. Timosaponin B II also induces neurotrophic factors and matrix effects, which are beneficial for the treatment of inflammatory conditions, neurodegenerative diseases, and metabolic disorders. The drug has been shown to have pharmacokinetic properties that are similar to those of timosaponin I. The molecular weight of the molecule was determined by LC-MS/MS analysis as 527.2 amu. Timosaponin B II is not metabolized by cytochrome P450 enzymes or glucuronidases, but it is hydrolyzed by esterases or glutathione reductase.Formula:C45H76O19Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:921.07 g/molβ-D-Galactopyranoside, (3β,5β,22α,25S)-26-(β-D-glucopyranosyloxy)-22-hydroxyfurostan-3-yl 2-O-β-D-glucopyranosyl-
CAS:Formula:C45H76O19Purezza:98%Colore e forma:SolidPeso molecolare:921.0735Timosaponin b ii
CAS:Natural glycosideFormula:C45H76O19Purezza:≥ 98.0 % (HPLC)Colore e forma:PowderPeso molecolare:921.09Timosaponin BII
CAS:Timosaponin BII has anti-diabetes, antioxidant, anti-inflammatory, and anti-dementia activities, it can significantly reduce the neurotoxicity induced by beta amyloid peptide 25-35 in primary neurons, the mechanism of which may be related with resisting oxidative damage and regulating the cholinergic system.Timosaponin BII can improve the neurological symptoms of cerebral ischemic rat, reduce infarct size, relieve brain water edema, improve hemorheology, reduce inflammatory injury of cerebral ischemia; it could be used in the preparation of a medicament or product for the prevention and treatment of stroke.Formula:C45H76O19Purezza:95%~99%Peso molecolare:921.084Timosaponin BII
CAS:Timosaponin BII combats dementia, treats type 2 diabetes, has antioxidant properties, and reduces BACE1 with retinal benefits.Formula:C45H76O19Purezza:100% - 99.98%Colore e forma:SolidPeso molecolare:921.07Ref: TM-T3394
1mg35,00€5mg70,00€10mg92,00€25mg150,00€50mg217,00€100mg324,00€500mg772,00€1mL*10mM (DMSO)130,00€
