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CAS 142439-99-4: 4-metilumbelliferile-7-(6-sulfo-2-*acetamido-2-de

Descrizione:
4-Metilumbelliferil-7-(6-sulfo-2-acetamido-2-desossido-α-D-glucopiranoside), comunemente riferito come un substrato fluorogenico, è un composto chimico utilizzato principalmente in saggi biochimici, in particolare per la rilevazione di enzimi specifici. Questo composto presenta un gruppo metilumbelliferil, noto per le sue proprietà fluorescenti, che consente una rilevazione sensibile quando viene scisso da enzimi come le glicosidasi. La presenza di un gruppo sulfonato ne migliora la solubilità in soluzioni acquose, rendendolo adatto per varie applicazioni biologiche. Inoltre, il gruppo acetamido contribuisce alla stabilità e specificità del substrato. Il composto è tipicamente utilizzato in contesti di ricerca per studiare la cinetica e l'attività enzimatica, fornendo uno strumento prezioso per comprendere il metabolismo dei carboidrati e le vie biochimiche correlate. La sua natura fluorescente consente il monitoraggio in tempo reale delle reazioni enzimatiche, rendendolo un reagente essenziale in biologia molecolare e biochimica. È necessario un corretto trattamento e condizioni di stoccaggio per mantenere la sua integrità ed efficacia nelle applicazioni sperimentali.
Formula:C18H20NNaO11S
InChI:InChI=1/C18H21NO11S.Na/c1-8-5-14(21)29-12-6-10(3-4-11(8)12)28-18-15(19-9(2)20)17(23)16(22)13(30-18)7-27-31(24,25)26;/h3-6,13,15-18,22-23H,7H2,1-2H3,(H,19,20)(H,24,25,26);/q;+1/p-1/t13-,15-,16-,17-,18-;/m1./s1
SMILES:Cc1cc(=O)oc2cc(ccc12)OC1C(C(C(C(COS(=O)(=O)O)O1)O)O)N=C(C)O.[Na]
Sinonimi:
  • sodium [(2R,3S,4R,5R,6S)-5-acetamido-3,4-dihydroxy-6-(4-methyl-2-oxo-chromen-7-yl)oxy-tetrahydropyran-2-yl]methyl sulfate
Ordinare per

5 prodotti.
  • 4-Methylumbelliferyl-N-acetyl-β-D-glucosaminide-6-sulfate, sodium salt

    CAS:
    4-Methylumbelliferyl 2-acetamido-2-deoxy-beta-D-glucopyranoside-6-sulfate sodium salt is a high-quality fluorogenic substrate specifically designed for the detection and quantification of various enzymes, including beta-glucosidases and sulfatases. Upon hydrolysis by the target enzyme, this substrate releases the highly fluorescent 4-methylumbelliferone, allowing for real-time monitoring and accurate measurement of enzyme activities in biochemical assays, diagnostic tests, and research applications. 4-Methylumbelliferyl 2-acetamido-2-deoxy-beta-D-glucopyranoside-6-sulfate sodium salt has excellent solubility in water, ensuring a consistent and reliable performance in different experimental conditions. This versatile substrate is an essential tool for researchers and industry professionals who require a sensitive and reproducible detection method for enzymes of interest.
    Formula:C18H20NNaO11S
    Purezza:Min. 98.0 Area-%
    Peso molecolare:481.41 g/mol

    Ref: 3D-M-5505

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  • 4-Methylumbelliferyl 2-Acetamido-2-deoxy-b-D-glucopyranoside 6-Sulphate Sodium Salt

    Prodotto controllato
    CAS:
    Applications 4-Methylumbelliferyl 2-acetamido-2-deoxy-b-D-glucopyranoside 6-sulphate sodium salt is a fluorescent substrate for isoenzyme A of N-acetyl-β-D-glucosaminidase (Hexosaminidase A). It can also be used in biological study of characterization of the mutant β-subunit of β-hexosaminidase for dimer formation responsible for the adult form of Sandhoff disease with the motor neuron disease phenotype. References Yamada, K., et al.: J Biochem, 153, 111 (2013)
    Formula:C18H21NO11S·Na
    Colore e forma:Neat
    Peso molecolare:482.41

    Ref: TR-M337660

    5mg
    292,00€
    10mg
    450,00€
  • 4-Methylumbelliferyl 2-acetamido-2-deoxy-b-D-glucopyranoside-6-sulfate sodium salt

    CAS:
    4-Methylumbelliferyl 2-acetamido-2-deoxy-beta-D-glucopyranoside-6-sulfate sodium salt is a high-quality fluorogenic substrate specifically designed for the detection and quantification of various enzymes, including beta-glucosidases and sulfatases. Upon hydrolysis by the target enzyme, this substrate releases the highly fluorescent 4-methylumbelliferone, allowing for real-time monitoring and accurate measurement of enzyme activities in biochemical assays, diagnostic tests, and research applications. 4-Methylumbelliferyl 2-acetamido-2-deoxy-beta-D-glucopyranoside-6-sulfate sodium salt has excellent solubility in water, ensuring a consistent and reliable performance in different experimental conditions. This versatile substrate is an essential tool for researchers and industry professionals who require a sensitive and reproducible detection method for enzymes of interest.
    Formula:C18H20NO11SNa
    Purezza:Min. 98 Area-%
    Colore e forma:White Powder
    Peso molecolare:481.41 g/mol

    Ref: 3D-EM03271

    10mg
    482,00€
    25mg
    973,00€
    50mg
    1.227,00€
    100mg
    1.638,00€
    250mg
    2.665,00€
  • 4-Methylumbelliferyl-2-acetamido-2-deoxy-6-sulphate-β-D-glucopyranoside sodium salt

    CAS:
    4-Methylumbelliferyl-2-acetamido-2-deoxy-6-sulphate-β-D-glucopyranoside sodium salt
    Formula:C18H20NO11S·Na
    Purezza:99% (by tlc) (Typical Value in Batch COA)
    Colore e forma: off white powder
    Peso molecolare:481.41g/mol

    Ref: 54-BIM1189

    25mg
    285,00€
    50mg
    448,00€
    100mg
    692,00€
  • Ref: 7W-GC5948

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