CAS: 1638211-05-8

TH287 is a research tool that acts as an activator of Ligand and Receptor. It is used in Cell Biology to study Protein interactions and Pharmacology for the treatment of peptides, life science, or inhibitor. The compound has high purity and is a ligand for ion channels. TH287 hydrochloride can be used as a research tool or as an activator in cell biology.

TH287 hydrochloride

TH287 inhibits MTH1 (IC50: 0.8 nM), causing DNA damage in cancer cells through oxidized dNTP incorporation, leading to cytotoxicity in mouse xenografts.