CAS: 1639220-17-9

Sigma-1 receptor antagonist 3 is a more potent and selective antagonist of Sigma-1 (σ1) receptor (Ki = 1.14 nM) than σ2 receptor(Ki = 1239 nM).

Sigma-1 receptor antagonist 3

5-Chloro-2-(4-fluorophenyl)-4-methyl-6-[3-(1-piperidinyl)propoxy]pyrimidine is a research tool that is used as an activator and ligand for various receptors. It has been shown to activate ion channels, such as calcium channels and sodium channels, and inhibit antibody production. This drug also binds to the extracellular domain of Ligand Receptor Complexes (LRCs) and inhibits cell proliferation by inhibiting protein synthesis. 5-Chloro-2-(4-fluorophenyl)-4-methyl-6-[3-(1-piperidinyl)propoxy]pyrimidine is a high purity compound with CAS No. 1639220-17-9.