CAS 173833-08-4: ostabolin
Descrizione:
ostabolin, identificato dal suo numero CAS 173833-08-4, è un composto sintetico che ha attirato l'attenzione nel campo della biochimica e della farmacologia. È principalmente noto per le sue potenziali proprietà anaboliche, che possono influenzare la crescita muscolare e la densità ossea. ostabolin è spesso classificato come un modulatore selettivo del recettore androgeno (SARM), il che significa che colpisce selettivamente i recettori androgeni nei tessuti muscolari e ossei, potenzialmente minimizzando gli effetti collaterali tipicamente associati agli steroidi anabolizzanti. Il composto è caratterizzato dalla sua capacità di promuovere l'attività anabolica riducendo al contempo gli effetti androgenici nei tessuti non bersaglio. Questa selettività lo rende un argomento di interesse per la ricerca su trattamenti per condizioni come la perdita muscolare e l'osteoporosi. Tuttavia, è importante notare che la sicurezza, l'efficacia e gli effetti a lungo termine di ostabolin negli esseri umani sono ancora sotto indagine e non è approvato per uso medico in molte regioni. Come con qualsiasi sostanza chimica da ricerca, si consiglia cautela riguardo al suo uso e alle potenziali implicazioni legali.
Formula:C162H270N50O46S2
InChI:InChI=1/C162H270N50O46S2/c1-21-86(18)130(211-143(240)101(42-47-124(223)224)190-154(251)117(75-215)207-157(254)127(83(12)13)208-133(230)93(168)73-213)159(256)193-100(41-45-119(170)217)139(236)197-107(60-80(6)7)145(242)191-103(49-56-259-19)141(238)202-112(65-89-71-178-77-184-89)149(246)204-113(66-120(171)218)150(247)195-105(58-78(2)3)134(231)182-72-122(220)185-95(35-24-27-51-163)135(232)201-111(64-88-70-177-76-183-88)148(245)198-108(61-81(8)9)146(243)203-114(67-121(172)219)151(248)206-116(74-214)155(252)194-104(50-57-260-20)160(257)258-126(227)48-43-102(192-156(253)128(84(14)15)209-142(239)98(38-31-55-180-162(175)176)187-132(229)92(167)39-46-123(221)222)140(237)200-110(63-87-69-181-94-34-23-22-32-90(87)94)147(244)199-109(62-82(10)11)153(250)212-158(255)129(85(16)17)210-152(249)115(68-125(225)226)205-138(235)99(40-44-118(169)216)189-144(241)106(59-79(4)5)196-137(234)97(37-26-29-53-165)188-136(233)96(36-25-28-52-164)186-131(228)91(166)33-30-54-179-161(173)174/h22-23,32,34,69-71,76-86,88-89,91-93,95-117,127-130,181,213-215H,21,24-31,33,35-68,72-75,163-168H2,1-20H3,(H2,169,216)(H2,170,217)(H2,171,218)(H2,172,219)(H,182,231)(H,185,220)(H,186,228)(H,187,229)(H,188,233)(H,189,241)(H,190,251)(H,191,242)(H,192,253)(H,193,256)(H,194,252)(H,195,247)(H,196,234)(H,197,236)(H,198,245)(H,199,244)(H,200,237)(H,201,232)(H,202,238)(H,203,243)(H,204,246)(H,205,235)(H,206,248)(H,207,254)(H,208,230)(H,209,239)(H,210,249)(H,211,240)(H,221,222)(H,223,224)(H,225,226)(H4,173,174,179)(H4,175,176,180)(H,212,250,255)/t86-,88?,89?,91-,92-,93-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,127-,128-,129-,130-/m0/s1
SMILES:CC[C@H](C)[C@@H](C(=N[C@@H](CCC(=N)O)C(=N[C@@H](CC(C)C)C(=N[C@@H](CCSC)C(=N[C@@H](CC1C=NC=N1)C(=N[C@@H](CC(=N)O)C(=N[C@@H](CC(C)C)C(=NCC(=N[C@@H](CCCCN)C(=N[C@@H](CC1C=NC=N1)C(=N[C@@H](CC(C)C)C(=N[C@@H](CC(=N)O)C(=N[C@@H](CO)C(=N[C@@H](CCSC)C(=O)OC(=O)CC[C@@H](C(=N[C@@H](Cc1c[nH]c2ccccc12)C(=N[C@@H](CC(C)C)C(=NC(=O)[C@H](C(C)C)N=C([C@H](CC(=O)O)N=C([C@H](CCC(=N)O)N=C([C@H](CC(C)C)N=C([C@H](CCCCN)N=C([C@H](CCCCN)N=C([C@H](CCCNC(=N)N)N)O)O)O)O)O)O)O)O)O)N=C([C@H](C(C)C)N=C([C@H](CCCNC(=N)N)N=C([C@H](CCC(=O)O)N)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)N=C([C@H](CCC(=O)O)N=C([C@H](CO)N=C([C@H](C(C)C)N=C([C@H](CO)N)O)O)O)O
Sinonimi:- Hpth-(1-31)NH2
- Human parathyroid hormone (1-31) amide
- L-Seryl-L-valyl-L-seryl-L-alpha-glutamyl-L-isoleucyl-L-glutaminyl-L-leucyl-L-methionyl-L-histidyl-L-asparaginyl-L-leucylglycyl-L-lysyl-L-histidyl-L-leucyl-L-asparaginyl-L-seryl-L-methionyl-L-alpha-glutamyl-L-arginyl-L-valyl-L-alpha-glutamyl-L-tryptophyl-L-leucyl-L-arginyl-L-lysyl-L-lysyl-L-leucyl-L-glutaminyl-L-alpha-aspartyl-L-valinamide
- Parathyroid hormone (1-31) amide
- Pth (1-31) amide
- L-Valinamide, L-seryl-L-valyl-L-seryl-L-alpha-glutamyl-L-isoleucyl-L-glutaminyl-L-leucyl-L-methionyl-L-histidyl-L-asparaginyl-L-leucylglycyl-L-lysyl-L-histidyl-L-leucyl-L-asparaginyl-L-seryl-L-methionyl-L-alpha-glutamyl-L-arginyl-L-valyl-L-alpha-glutamyl-L-tryptophyl-L-leucyl-L-arginyl-L-lysyl-L-leucyl-L-glutaminyl-L-alpha-aspartyl-
Ordinare per
3 prodotti.
Parathyroid Hormone (Human, 1-31 Amide)
CAS:This product which is available as a 0.5mg vial is amino acids 1-31 of the 84 amino acid parathyroid hormone (PTH) and can be used as an adenylate cyclase and bone growth stimulating peptide. PTH is a peptide hormone that is secreted from the parathyroid gland in the event of abnormal serum calcium levels and it ultimately regulates calcium and phosphate levels in the body. The PTH exerts its activity through binding to the G-protein coupled receptor type 1 PTH receptor, which activates adenylate cyclase or phospholipase C thus activating pathways involved in the mediation of bone resorption and bone formation. This product is suitable for life science applications.Formula:C162H270N50O46S2Purezza:Min. 95%Peso molecolare:3,718.3 g/molpTH (1-31) amide (human)
CAS:pTH (1-31) amide appears so far to be the smallest of the potently osteogenic pTH fragments. The osteogenic activity of this pTH fragment seems to be related to its ability to activate adenylyl cyclase. Unlike pTH, this fragment does not activate phospholipase C and should therefore have fewer side-effects and find application in the osteoporosis treatment.Formula:C162H270N50O46S2Purezza:96.7%Peso molecolare:3718.37pTH (1-31) amide (human)
CAS:pTH (1-31) amide is a polymer conjugate that is used to treat osteoporosis. It has been shown to be effective in reducing the risk of fracture and increasing bone mineral density in animals. The compound binds to the extracellular domain of the estrogen receptor, altering its conformation and preventing it from interacting with other proteins in the nucleus. pTH (1-31) amide has also been shown to reduce blood pressure in animals by inhibiting angiotensin-converting enzyme. Clinical data on this drug are limited, but it has been well tolerated so far.Formula:C162H270N50O46S2Purezza:Min. 95%Peso molecolare:3,718.32 g/mol
