CAS: 21269-37-4

Tiopronin disulfide is a peptide that is an activator of ion channels. It has been shown to inhibit the activity of Ca2+ channels, which are protein complexes that regulate the influx of calcium ions into cells. Tiopronin disulfide has also been shown to activate K+ channels, which are protein complexes that regulate potassium ion flow in and out of cells. Tiopronin disulfide can be used as a research tool for studying protein interactions and as a pharmacological tool in the development of new drugs.

Stability Very Hygroscopic Applications Tiopronin Disulfide is used in the treatment of mitochondrial dysfunction and postischemic myocardial damage. Tiopronin Disulfide partly prevents and reverses mitochondrial uncoupling and improves deteriorated heart function. References Fuchs, J., et. al.: Arzneimittel-Forschung, 35, 1394 (1985)