CAS: 2138882-71-8

Kea1-97 is a selective disruptor of interaction between thioredoxin and caspase-3 (IC50 = 10 μ M).

4,6-Dichloro-N-(4'-Fluoro-[1,1'-Biphenyl]-4-Yl)-1,3,5-Triazin-2-Amine

KEA1-97 is a small molecule that inhibits autophagy. It binds to reactive lysines present in the active site of the protein kinase, blocking the ability of this enzyme to phosphorylate amino acids. This prevents the tumor suppressor proteins from being degraded and prevents cell death from occurring. KEA1-97 is a reversible covalent inhibitor that can be taken orally and does not have any known side effects.

KEA1-97