CAS 21967-41-9: Baicalina
Descrizione:
Baicalina è un glicoside flavonoide derivato dalle radici di Scutellaria baicalensis, una pianta comunemente usata nella medicina tradizionale cinese. La sua struttura chimica consiste in uno scheletro di flavone con un gruppo di acido glucuronico, che contribuisce alla sua solubilità e bioattività. Baicalina è noto per le sue varie proprietà farmacologiche, inclusi effetti antinfiammatori, antiossidanti e neuroprotettivi. È stato studiato per le sue potenziali applicazioni terapeutiche in condizioni come ansia, depressione e malattie neurodegenerative. Il composto presenta un profilo di tossicità relativamente basso, rendendolo un candidato per ulteriori ricerche in chimica medicinale. Baicalina è tipicamente caratterizzato dal suo colore giallastro ed è solubile in acqua e alcol, ma meno in solventi non polari. Il suo meccanismo d'azione coinvolge la modulazione di varie vie di segnalazione, comprese quelle relative allo stress ossidativo e all'infiammazione. In generale, Baicalina rappresenta un'area di interesse significativa sia nella chimica dei prodotti naturali che nella farmacologia grazie alle sue diverse attività biologiche e potenziali benefici per la salute.
Formula:C21H18O11
InChI:InChI=1S/C21H18O11/c22-9-6-10(8-4-2-1-3-5-8)30-11-7-12(14(23)15(24)13(9)11)31-21-18(27)16(25)17(26)19(32-21)20(28)29/h1-7,16-19,21,23-27H,(H,28,29)/t16-,17-,18+,19-,21+/m0/s1
InChI key:InChIKey=IKIIZLYTISPENI-ZFORQUDYSA-N
SMILES:OC1=C2C(OC(=CC2=O)C3=CC=CC=C3)=CC(O[C@@H]4O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]4O)=C1O
Sinonimi:- 5,6-Dihydroxy-4-oxo-2-phenyl-4H-1-benzopyran-7-yl β-<span class="text-smallcaps">D</span>-glucopyranosiduronic acid
- 5,6-Dihydroxy-4-oxygen-2-phenyl-4H-1-benzopyran-7-beta-D-glucopyranose acid
- 5,6-dihydroxy-4-oxo-2-phenyl-4H-chromen-7-yl beta-D-glucopyranosiduronic acid
- 5,6-dihydroxy-4-oxo-2-phenyl-4H-chromen-7-yl hexopyranosiduronic acid
- Baicalein 7-O-glucuronide
- Baicalein 7-O-β-<span class="text-smallcaps">D</span>-glucuronide
- Baicalein 7-glucuronide
- β-<span class="text-smallcaps">D</span>-Glucopyranosiduronic acid, 5,6-dihydroxy-4-oxo-2-phenyl-4H-1-benzopyran-7-yl
- Baicalin
- 5,6-Dihydroxy-4-oxo-2-phenyl-4H-1-benzopyran-7-yl β-D-glucopyranosiduronic acid
- β-D-Glucopyranosiduronic acid, 5,6-dihydroxy-4-oxo-2-phenyl-4H-1-benzopyran-7-yl
- Vedi altri sinonimi
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17 prodotti.
(2S,3S,4S,5R,6S)-6-[(4,6-dihydroxy-5-oxo-2-phenyl-5H-chromen-7-yl)oxy]-3,4,5-trihydroxyoxane-2-carboxylic acid
CAS:Purezza:95%Peso molecolare:446.364013671875Ref: 10-F808019
5gPrezzo su richiesta10gPrezzo su richiesta25g49,00€50gPrezzo su richiesta100g143,00€Baicalin 7-b-D-glucuronide
CAS:Baicalin 7-b-D-glucuronide is a flavonoid metabolite, which is primarily derived from the root of the plant *Scutellaria baicalensis*, commonly known as Chinese skullcap. This compound occurs as part of the extensive array of flavonoids in traditional medicinal plants used in various ethnic medicine systems. Baicalin 7-b-D-glucuronide exerts its biological effects through multiple mechanisms of action, primarily involving its interaction with cellular pathways related to inflammation and oxidative stress. It is known to inhibit the production of pro-inflammatory cytokines and enzymes by modulating signaling pathways such as NF-κB and MAPK. Additionally, it has been shown to scavenge free radicals, thereby exerting antioxidant effects. The primary applications of Baicalin 7-b-D-glucuronide are in research related to its potential therapeutic uses, including its roles in anti-inflammatory, antioxidant, and neuroprotective strategies. It holds promise in the investigation of treatments for conditions such as inflammatory diseases, neurodegenerative disorders, and potentially in oncology, due to its ability to influence cellular homeostasis and prevent oxidative damage. As such, it serves as a significant compound of interest in the development of novel therapeutic agents.Formula:C21H18O11Purezza:Min. 95 Area-%Colore e forma:White PowderPeso molecolare:446.36 g/molBaicalin
CAS:Natural glycosideFormula:C21H18O11Purezza:≥ 90.0 % (HPLC)Colore e forma:PowderPeso molecolare:446.37Baicalin
CAS:This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Formula:C21H18O11Colore e forma:Powder or crystals, White to yellowPeso molecolare:446.36Baicalin
CAS:Baicalin is a flavonoid and a major component of a herbal medicine, Sho-saiko-to, which is commonly used for treatment of chronic hepatitis in Japan and China. baicalin acts as anti-oxidants, also causes cytotoxic effect,and induces caspase-3 activation and apoptosis via mitochondrial pathway.Formula:C21H18O11Purezza:95%~99%Colore e forma:Yellow powderPeso molecolare:446.364Baicalein 7-O-Glucuronide
CAS:Other glycosides, natural or reproduced by synthesis, and their salts, ethers, esters and other derivativesFormula:C21H18O11Colore e forma:Yellow PowderPeso molecolare:446.08491Baicalin
CAS:Formula:C21H18O11Purezza:>90.0%(T)Colore e forma:White to Yellow powder to crystalPeso molecolare:446.36Baicalin
CAS:Baicalin analytical standard provided with w/w absolute assay, to be used for quantitative titration.Formula:C21H18O11Purezza:(HPLC) ≥99%Colore e forma:PowderPeso molecolare:446.36(2S,3S,4S,5R,6R)-6-(5,6-dihydroxy-4-oxo-2-phenylchromen-7-yl)oxy-3,4,5-trihydroxyoxane-2-carboxylic acid
CAS:Formula:C21H18O11Purezza:90%Colore e forma:SolidPeso molecolare:446.36102Baicalin 7-b-D-glucuronide
CAS:Formula:C21H18O11Purezza:≥ 95.0%Colore e forma:White, off-white or yellow powderPeso molecolare:446.36Baicalin
CAS:Prodotto controllatoStability Hygroscopic Applications Baicalin, Baicalin is the glucuronide of Baicalein (B115250). Baicalin is a known prolyl endopeptidase inhibitor, induces apoptosis in pancreatic cancer cells,[3] and affects the GABA receptors. References Tarrago, T., et al.: Bioorg. Med. Chem, 16 (15), 7516 (2008); Takahashi, H., et al.: Biochim Biophys Acta, 1813 (8), 1465 (2011);Formula:C21H18O11Colore e forma:NeatPeso molecolare:446.36Baicalin
CAS:Baicalin (Baicalein 7-O-β-D-glucuronide) is a prolyl endopeptidase inhibitor isolated from scutellaria baicalensis, with antioxidant, anti-tumor, anti-HIVFormula:C21H18O11Purezza:90.08% - 99.25%Colore e forma:Yellow PowderPeso molecolare:446.36
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