CAS: 2237268-08-3

SBI-797812

SBI-797812 is structurally similar to active-site directed inhibitor of NAMPT(NAMPT with EC50 of 0.37 μM).

SBI-797812 is a small molecule that targets the cellular protein, stabilin-1. It has been shown to suppress the degradation of stabilin-1 and stabilize it in cells from animals and humans. When this drug binds to stabilin-1, it prevents the binding of destabilizing molecules and increases the stability of stabilin-1. This drug also has been shown to boost levels of stabilin-1 in tissues from mice by increasing the biosynthesis of mononucleotides. SBI-797812 has potential as a treatment for diseases such as Parkinson's disease, Alzheimer's disease, Huntington's disease, and amyotrophic lateral sclerosis.