CAS: 2271036-44-1

Pomalidomide-PEG1-C2-N3 is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Pomalidomide-PEG1-C2-N3 is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

Pomalidomide-PEG1-C2-N3: A cereblon ligand for CDK6 PROTAC degrader CP-10, with a PEG linker; has a DC50 of 2.1 nM for degrading CDK6.