CAS 29868-97-1: Cloridrato di pirenzepina
Descrizione:
Cloridrato di pirenzepina è un composto sintetico classificato principalmente come un agente antimuscarinico, il che significa che inibisce selettivamente l'azione dell'acetilcolina sui recettori muscarinici. Questa caratteristica lo rende utile nel trattamento di vari disturbi gastrointestinali, in particolare le ulcere peptiche, riducendo la secrezione di acido gastrico. La sostanza è tipicamente presentata come una polvere cristallina bianca o bianco sporco, solubile in acqua e con un intervallo di pH generalmente neutro. La sua struttura chimica include un anello di piridina, contribuendo alle sue proprietà farmacologiche. Cloridrato di pirenzepina è noto per il suo profilo di effetti collaterali relativamente basso rispetto ad altri farmaci anticolinergici, rendendolo una scelta preferita in determinati contesti terapeutici. Inoltre, è stato studiato per potenziali applicazioni oltre ai problemi gastrointestinali, inclusi i suoi effetti sul sistema nervoso centrale. Come per qualsiasi medicinale, il suo uso dovrebbe essere guidato da un professionista sanitario, considerando possibili interazioni e controindicazioni.
Formula:C19H21N5O2·2ClH
InChI:InChI=1S/C19H21N5O2.2ClH/c1-22-9-11-23(12-10-22)13-17(25)24-16-7-3-2-5-14(16)19(26)21-15-6-4-8-20-18(15)24;;/h2-8H,9-13H2,1H3,(H,21,26);2*1H
InChI key:InChIKey=FFNMBRCFFADNAO-UHFFFAOYSA-N
SMILES:C(CN1CCN(C)CC1)(=O)N2C=3C(NC(=O)C=4C2=CC=CC4)=CC=CN3.Cl
Sinonimi:- 11-[(4-methylpiperazin-1-yl)acetyl]-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one dihydrochloride
- 11-[2-(4-methylpiperazin-1-yl)acetyl]-5H-pyrido[2,3-b][1,4]benzodiazepin-6-one hydrate hydrochloride
- 5,11-Dihydro-11-((4-methylpiperazin-1-yl)acetyl)-6H-pyrido(2,3-b)-(1,4)benzodiazepin-6-one dihydrochloride
- 5,11-Dihydro-11-[(4-methyl-1-piperazinyl)acetyl]-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one dihydrochloride
- 6H-Pyrido[2,3-b][1,4]benzodiazepin-6-one, 5,11-dihydro-11-[(4-methyl-1-piperazinyl)acetyl]-, dihydrochloride
- 6H-Pyrido[2,3-b][1,4]benzodiazepin-6-one, 5,11-dihydro-11-[2-(4-methyl-1-piperazinyl)acetyl]-, hydrochloride (1:2)
- Duogastral
- Durapirenz
- Gasteril
- Gastricur
- Gastrozepin
- Vedi altri sinonimi
Ordinare per
12 prodotti.
PIRENZEPINE DIHYDROCHLORIDE MONOHYDRATE CRS
CAS:PIRENZEPINE DIHYDROCHLORIDE MONOHYDRATE CRSFormula:C19H23Cl2N5O2Colore e forma:Crystalline Powder. White. Light Yellow. Powder., Crystalline Powder. White. Light Yellow. Powder.Peso molecolare:424.3242Pirenzepine dihydrochloride
CAS:Formula:C19H21N5O2·2HClPurezza:98.0 - 102.0 % (dried basis)Colore e forma:White to off-white or pale yellow powderPeso molecolare:424.32Pirenzepine dihydrochloride
CAS:Pirenzepine is a nonsteroidal anti-inflammatory drug and prokinetic agent used to treat bowel disease. It is also used to treat pancreatic enzyme deficiency, which can result in chronic diarrhea. Pirenzepine has been shown to inhibit protease activity in mouse serum, and it has been reported that this inhibition may be due to its ability to bind with amyloid protein and prevent amyloid aggregation. Pirenzepine also suppresses inflammatory responses by inhibiting the production of inflammatory mediators such as leukotrienes, prostaglandins, and cytokines, thereby providing therapeutic benefits for treating chronic bronchitis and other inflammatory diseases. Pirenzepine is metabolized in the liver by the cytochrome P450 enzyme system into an active form called pirenzepine N-oxide. This active form is then metabolized by hydrolysis or glucuronidation before excretion from the body. The most common sideFormula:C19H23Cl2N5O2Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:424.32 g/molPirenzepine-d8 Dihydrochloride
CAS:Prodotto controllatoFormula:C19H15D8Cl2N5O2Colore e forma:NeatPeso molecolare:432.37Pirenzepine Dihydrochloride
CAS:Formula:C19H21N5O2·2HClPurezza:>98.0%(T)(HPLC)Colore e forma:White to Yellow to Orange powder to crystalPeso molecolare:424.33Pirenzepine dihydrochloride
CAS:Formula:C19H23Cl2N5O2Purezza:%Colore e forma:SolidPeso molecolare:424.3242Pirenzepine-d10 Dihydrochloride
CAS:Prodotto controllatoApplications Pirenzepine-d10 Dihydrochloride is an analogue of Pirenzepine (P508500), an antiucerative agent that works by inhibiting tricyclic gastric-acid secretion. References Fliri, A . F., et al.: J. Med. Chem., 52, 8038 (2009); Eberlein, W., et al.: Arzneimittel-Forsch., 27, 356 (1977), Hellerr, G., et al.: Verh. Deut. Ges. Inn. Med., 84, 991 (1978), Carmine, A.A., et al.: Drugs, 30,85 (1985), El-Obeid, H.A., et al.: Anal. Profiles Drug Subs., 16, 445 (1987), Homon, C.A., et al.: Ther. Drug Monit., 9, 236 (1987),Formula:C19H12D11Cl2N5O2Colore e forma:BrownPeso molecolare:435.39Pirenzepine, Dihydrochloride
CAS:Prodotto controllatoApplications An antiulcerative. Tricyclic gastric-acid inhibitor. References Eberlein, W., et al.: Arzneimittel-Forsch., 27, 356 (1977), Hellerr, G., et al.: Verh. Deut. Ges. Inn. Med., 84, 991 (1978), Carmine, A.A., et al.: Drugs, 30,85 (1985), El-Obeid, H.A., et al.: Anal. Profiles Drug Subs., 16, 445 (1987), Homon, C.A., et al.: Ther. Drug Monit., 9, 236 (1987),Formula:C19H21N5O2·2ClHColore e forma:NeatPeso molecolare:424.32Pirenzepine dihydrochloride, 99%
CAS:A M1 muscarinic receptor antagonist This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Formula:C19H23Cl2N5O2Purezza:99%Colore e forma:Crystals or powder or crystalline powder, White to pale yellowPeso molecolare:424.33
