CAS 36791-04-5: Ribavirina
Descrizione:
Ribavirina è un farmaco antivirale utilizzato principalmente per trattare infezioni virali, in particolare l'epatite C e il virus respiratorio sinciziale (VRS). È classificato come un analogo dei nucleosidi, il che significa che imita i mattoni costitutivi dell'RNA e del DNA, interferendo così con la replicazione virale. La formula chimica di Ribavirina è C₁₁H₁₅N₄O₅P, e presenta una struttura simile alla guanosina che gli consente di inibire la sintesi dell'RNA virale. Ribavirina viene spesso somministrato in combinazione con altri agenti antivirali per aumentarne l'efficacia. La sostanza è tipicamente presentata come una polvere cristallina bianca o bianco sporco, solubile in acqua e leggermente solubile in alcol. Il suo meccanismo d'azione implica l'inibizione della RNA polimerasi virale e l'induzione di mutagenesi nei genomi virali, portando alla produzione di particelle virali difettose. Sebbene sia efficace, Ribavirina può avere effetti collaterali, tra cui anemia emolitica ed effetti teratogeni, richiedendo un attento monitoraggio durante il trattamento. A causa della sua azione specifica contro i virus a RNA, Ribavirina rimane un componente critico nella gestione di alcune infezioni virali.
Formula:C8H12N4O5
InChI:InChI=1S/C8H12N4O5/c9-6(16)7-10-2-12(11-7)8-5(15)4(14)3(1-13)17-8/h2-5,8,13-15H,1H2,(H2,9,16)/t3-,4-,5-,8-/m1/s1
InChI key:InChIKey=IWUCXVSUMQZMFG-AFCXAGJDSA-N
SMILES:O[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N2N=C(C(N)=O)N=C2
Sinonimi:- 1-Beta-D-Ribofuranosyl-1,2,4-Triazole-3-Carboxamide
- 1-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-1,2,4-triazole-3-carboxamide
- 1-pentofuranosyl-1H-1,2,4-triazole-3-carboxamide
- 1-β-<span class="text-smallcaps">D</span>-Ribofuranosyl-1,2,4-triazol-3-carboxyamide
- 1-β-<span class="text-smallcaps">D</span>-Ribofuranosyl-1,2,4-triazole-3-carboxamide
- 1-β-<span class="text-smallcaps">D</span>-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide
- 1-β-D-Ribofuranosyl-1,2,4-triazol-3-carboxyamide
- 1-β-D-ribofuranosyl-1,2,4-triazole-3-carboxamide
- 1H-1,2,4-Triazole-3-carboxamide, 1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-
- 1H-1,2,4-Triazole-3-carboxamide, 1-β-D-ribofuranosyl-
- Biopolymers
- Vedi altri sinonimi
Ordinare per
Ribavirin 100 µg/mL in Acetonitrile:Methanol
CAS:Prodotto controllatoFormula:C8H12N4O5Colore e forma:Single SolutionPeso molecolare:244.20Ribavirin
CAS:Ribavirin (Tribavirin) is a synthetic nucleoside analog of ribofuranose with activity against hepatitis C virus and other RNA viruses.Formula:C8H12N4O5Purezza:98.53% - 99.83%Colore e forma:Less Solid Colourless SolidPeso molecolare:244.2Ribavirin, 98%
CAS:This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Formula:C8H12N4O5Purezza:98%Colore e forma:White to off-white, PowderPeso molecolare:244.21Ribavirin
CAS:RibavirinFormula:C8H12N4O5Purezza:99.9%Colore e forma:White SolidPeso molecolare:244.08077Ribavirin
CAS:Prodotto controllatoRibavirin is a guanosine nucleoside analog with broad-spectrum antiviral properties. Ribavirin gets phosphorylated to ribavirin triphosphate in cells and competes with natural nucleotides for incorporation in a nascent RNA chain, thus interfering with RNA synthesis by inhibiting viral RNA polymerases. Ribavirin is also an inhibitor of inosinate dehydrogenase (IMP), which is involved in the biosynthesis of GTP.Formula:C8H12N4O5Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:244.2 g/molRibavirin
CAS:Formula:C8H12N4O5Purezza:>98.0%(HPLC)(N)Colore e forma:White to Almost white powder to crystalPeso molecolare:244.21Ribavirin, Antibiotic for Culture Media Use Only
CAS:Prodotto controllatoRibavirin is an antiviral agent used for the treatment of hepatitis C, respiratory syncytial virus infection and influenza. It is a monocarboxylic acid derived from vitamin B2. Ribavirin inhibits viral replication by interfering with the function of RNA polymerase. Ribavirin also has immunosuppressive properties that can be useful in treating autoimmune disorders such as systemic lupus erythematosus and it has been approved by the FDA for treatment of chronic hepatitis C virus (HCV) genotype 1 infection with compensated liver disease or decompensated liver disease with or without HCV genotype 3 infection. The antiviral activity of ribavirin against other viruses, including HIV-1, herpes simplex virus type 2, varicella zoster virus, cytomegalovirus, respiratory syncytial virus, influenza A and B viruses has been reported but not largely studied.Formula:C8H12N4O5Purezza:Min. 97.0 Area-%Peso molecolare:244.20 g/molRef: 3D-Q-201670
1kgPrezzo su richiesta100gPrezzo su richiesta250gPrezzo su richiesta500gPrezzo su richiesta2500gPrezzo su richiesta-Unit-ggPrezzo su richiestaRibavirin
CAS:Formula:C8H12N4O5Purezza:≥ 98.0% (dried basis)Colore e forma:White to off-white powderPeso molecolare:244.20Ribavirin
CAS:RibavirinFormula:C8H12N4O5Purezza:99.97% (Typical Value in Batch COA)Colore e forma: white solidPeso molecolare:244.20g/molRibavirin
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormula:C8H12N4O5Colore e forma:White Crystalline PowderPeso molecolare:244.21 g/molRibavirin
CAS:Prodotto controllatoApplications Purine nucleoside analog; inhibits inosine monophosphate dehydrogenase (IMPDH). Used as an antiviral agent.This compound is suitable for pyruvate dehydrogenase (PDH) related research. References Fernandez, H., et al.: Eur. J. Epidemiol., 2, 1 (1986), Liao, H.J. and Stollar, V.: Antiviral Res., 22, 285 (1993), Honda, Y., et al.: Antimicrob. Agents Chemother., 38, 653 (1994), Reichard, O., et al.: Lancet, 351, 83 (1998)Formula:C8H12N4O5Colore e forma:WhitePeso molecolare:244.201-β-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide
CAS:Formula:C8H12N4O5Purezza:98%Colore e forma:SolidPeso molecolare:244.2047
