CAS 3902-71-4: Trimetilpsoralene
Descrizione:
Trimetilpsoralene (TMP) è un composto chimico appartenente alla classe dei psoraleni, noti per la loro capacità di intercalarsi con il DNA e formare legami incrociati quando esposti alla luce ultravioletta (UV). È caratterizzato dalla sua struttura molecolare, che include tre gruppi metilici attaccati al nucleo del psoralene, migliorando la sua solubilità e reattività. TMP è tipicamente un solido cristallino incolore o giallo pallido ed è solubile in solventi organici come etanolo e dimetilsolfossido (DMSO), ma ha una solubilità limitata in acqua. Questo composto è utilizzato principalmente nella fototerapia, in particolare per trattare condizioni della pelle come psoriasi e vitiligine, poiché potenzia gli effetti della terapia con luce UV. Inoltre, TMP ha applicazioni nella ricerca, in particolare in studi che coinvolgono interazioni del DNA e fotobiologia. A causa delle sue proprietà fotosensibilizzanti, si consiglia cautela nella manipolazione di TMP, poiché può causare sensibilizzazione della pelle e altri effetti avversi in caso di esposizione alla luce UV.
Formula:C14H12O3
InChI:InChI=1S/C14H12O3/c1-7-4-12(15)17-14-9(3)13-10(6-11(7)14)5-8(2)16-13/h4-6H,1-3H3
InChI key:InChIKey=FMHHVULEAZTJMA-UHFFFAOYSA-N
SMILES:CC=1C2=C(C=C3C1OC(C)=C3)C(C)=CC(=O)O2
Sinonimi:- 5-Benzofuranacrylic acid, 6-hydroxy-β,2,7-trimethyl-, δ-lactone
- 4,5′,8-Trimethylpsoralen
- 2,5,9-Trimethyl-7H-furo[3,2-g][1]benzopyran-7-one
- Trioxsalen
- 7H-Furo[3,2-g][1]benzopyran-7-one, 2,5,9-trimethyl-
Ordinare per
15 prodotti.
Trioxsalen
CAS:Formula:C14H12O3Purezza:>98.0%(HPLC)Colore e forma:White to Light yellow powder to crystalPeso molecolare:228.254,5',8-Trimethylpsoralen, 99%
CAS:4,5',8-Trimethylpsoralen is used for treatment of psoriasis, and as a photochemical crosslinker of DNA used as a probe for nucleic acid structure, used to crosslink DNA onto mica surfaces, mutagenesis of N2 worms. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Formula:C14H12O3Purezza:99%Peso molecolare:228.25Trioxsalen (DISCONTINUED)
CAS:Aromatic heterocyclic pesticides with oxygen hetero-atom(s) only, nesoiFormula:C14H12O3Colore e forma:White CrystalsPeso molecolare:228.078644,5',8-Trimethylpsoralen, 97.5%
CAS:This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Formula:C14H12O3Purezza:97.5%Colore e forma:Crystalline powder, White to light beigePeso molecolare:228.25Trioxsalen
CAS:LactoneFormula:C14H12O3Purezza:≥ 90.0 % (HPLC)Colore e forma:PowderPeso molecolare:228.25Trioxsalen
CAS:Trioxsalen (Trioxysalen) is a furanocoumarin and a psoralen derivative, in conjunction with UV-A for phototherapy treatment of vitiligo and hand eczema.Formula:C14H12O3Purezza:98.96% - 99.41%Colore e forma:Crystalline PowderPeso molecolare:228.242,5,9-trimethyl-7H-furo[3,2-g]chromen-7-one
CAS:Purezza:99.0%Colore e forma:SolidPeso molecolare:228.2469940185547Ref: 4Z-T-434001
5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaTrioxysalen
CAS:Prodotto controllatoApplications Trioxysalen, is used for visualization of genomic interstrand cross-links localized by laser photoactivation. It has been also been used to crosslink DNA onto mica surfaces. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Thazhathveetill, et al.: Bioconjugare Chem., 18 (2), 431 (2007); Musdal, Y., et al.: Chem. Bio. Interac., 205, 53 (2013);Formula:C14H12O3Colore e forma:NeatPeso molecolare:228.244,5',8-Trimethylpsoralen
CAS:4,5',8-Trimethylpsoralen is a fatty acid that can be synthesized from para-aminobenzoic acid. It has been shown to have carcinogenic potential in vitro and in vivo. 4,5',8-Trimethylpsoralen inhibits transcription by binding to DNA polymerase II and III. This inhibition prevents the production of RNA and protein synthesis, leading to cell death. 4,5',8-Trimethylpsoralen also inhibits DNA synthesis by binding to the enzyme DNA gyrase and topoisomerase IV. It is not active against some bacteria that are resistant to other drugs due to the presence of mutations in their genes encoding for the target enzymes. 4,5',8-Trimethylpsoralen has been shown to inhibit autoimmune diseases such as arthritis and lupus erythematosus.br>br>4,5',8-Trimethylpsoralen is most commonly used asFormula:C14H12O3Purezza:Min. 95%Colore e forma:PowderPeso molecolare:228.24 g/mol
![2,5,9-trimethyl-7H-furo[3,2-g]chromen-7-one](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb%2FF358125.jpg&w=3840&q=75)
