CAS: 566940-03-2

(R)-(-)-5,5'-Bis[di(3,5-di-t-butyl-4-methoxyphenyl)phosphino]-4,4'-bi-1,3-benzodioxole, min. 98% (R)-(-)-DTBM-SEGPHOS®

(R)-5,5Õ-Bis[Di(3,5-Di-Tert-Butyl-4-Methoxyphenyl)Phosphino]-4,4Õ-Bi-1,3-Benzodioxole

(R)-(-)-5,5'-Bis[di(3,5-di-t-butyl-4-methoxyphenyl)phosphino]-4,4'-bi-1,3-benzodioxole is a yellow solid with a molecular weight of 514.7. It has a melting point of 189°C and is soluble in organic solvents. (R)-(-)-5,5'-Bis[di(3,5-di-t-butyl-4-methoxyphenyl)phosphino]-4,4'-bi-1,3-benzodioxole is used as an inhibitor of the enzyme β-(1->2) diketone reductase from the fungus Candida albicans. The compound binds to copper oxide in the active site and blocks access to the substrate. This inhibits the enzymatic reaction between phenyl groups and alkene substr