CAS 67-20-9: Furantoina
Descrizione:
Furantoina, noto anche come nitroFurantoina, è un antibiotico utilizzato principalmente per trattare le infezioni del tratto urinario. Appartiene alla classe dei composti nitrofuranici e presenta un'attività antibatterica ad ampio spettro contro vari batteri Gram-positivi e Gram-negativi. La struttura chimica di Furantoina presenta un anello nitrofuranico, essenziale per le sue proprietà antimicrobiche. Agisce inibendo la sintesi delle proteine batteriche, del DNA, dell'RNA e della sintesi della parete cellulare, portando infine alla morte cellulare batterica. Furantoina viene tipicamente somministrato per via orale ed è ben assorbito nel tratto gastrointestinale, con la sua efficacia aumentata se assunto con cibo. Gli effetti collaterali comuni possono includere disturbi gastrointestinali, reazioni allergiche e, in rari casi, tossicità polmonare. A causa del suo specifico meccanismo d'azione e farmacocinetica, Furantoina è particolarmente efficace per le infezioni del tratto urinario non complicate causate da organismi suscettibili. Tuttavia, non è adatto per infezioni sistemiche o quelle causate da alcuni batteri resistenti. Come per qualsiasi farmaco, è importante utilizzare Furantoina sotto la guida di un professionista sanitario per garantire un uso appropriato e ridurre al minimo i potenziali effetti collaterali.
Formula:C8H6N4O5
InChI:InChI=1S/C8H6N4O5/c13-6-4-11(8(14)10-6)9-3-5-1-2-7(17-5)12(15)16/h1-3H,4H2,(H,10,13,14)
InChI key:InChIKey=NXFQHRVNIOXGAQ-UHFFFAOYSA-N
SMILES:N(=CC=1OC(N(=O)=O)=CC1)N2CC(=O)NC2=O
Sinonimi:- 1-(5-Nitro-2-furfurylidenamino)hydantoin
- 1-(5-Nitro-2-furfurylideneamino)hydantoin
- 1-(5-Nitrofurfurylideneamino)Hydantoin
- 1-[(5-Nitrofuran-2-yl)methylideneamino]imidazolidine-2,4-dione
- 1-[(5-Nitrofurfurylidene)amino]hydantoin
- 1-[[(5-Nitro-2-furanyl)methylene]amino]-2,4-imidazolidinedione
- 1-[[(5-Nitro-2-furyl)methylene]amino]-2,4-imidazolidinone
- 1-{[(5-Nitrofuran-2-Yl)Methylidene]Amino}Imidazolidine-2,4-Dione
- 2,4-Imidazolidinedione, 1-[[(5-nitro-2-furanyl)methylene]amino]-
- 5-Nitrofurantoin
- Berkfurin
- Vedi altri sinonimi
Ordinare per
Nitrofurantoin
CAS:Prodotto controllatoApplications A nitrofuran antibiotic with low resistance potential that is rapidly metabolized by mammals. Active against both Gram-positive and Gram-negative bacteria. Nitrofurantoin is also a prooxidant that is cytotoxic due to the generation of intracellular H2O2. Antibacterial.Environmental contaminants; Food contaminants; Heat processing contaminants References Cadwallader, D.E., et al.: Anal. Profiles Drug Subs., 5, 345 (1976), Rogers, R.G., et al.: Am. J. Obstr. Gynecol., 191, 182 (2004),Formula:C8H6N4O5Colore e forma:Light Yellow To YellowPeso molecolare:238.16Nitrofurantoin - Bio-X ™
CAS:Nitrofurantoin is an antibiotic that binds to the bacterial ribosome and inhibits protein synthesis. It is used to treat a wide range of infections, including urinary tract infections and its common causes such as E. coli, Citrobacter and Enterococcus. Nitrofurantoin is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.Formula:C8H6N4O5Purezza:Min. 95%Colore e forma:PowderPeso molecolare:238.16 g/molNitrofurantoin, 98%
CAS:This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Purezza:98%Colore e forma:Yellow, PowderRef: 4Z-N-341
5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaNitrofurantoin
CAS:Formula:C8H6N4O5Purezza:≥ 98.0% (anhydrous basis)Colore e forma:Yellow crystalline powderPeso molecolare:238.16Nitrofurantoin
CAS:Nitrofurantoin is an antimicrobial agent, which is a synthetic chemical compound with bactericidal activity. Its source is synthetic, originating from the nitrofuran class of compounds. Nitrofurantoin's mode of action involves the inhibition of essential bacterial enzymes. It is reduced by bacterial flavoproteins to active intermediates, which subsequently alter or disrupt ribosomal proteins, DNA, and other vital macromolecules within bacterial cells, thereby inhibiting key metabolic processes. Nitrofurantoin is most commonly used in the treatment and prophylaxis of uncomplicated urinary tract infections (UTIs). Its effectiveness is primarily restricted to the urinary tract because it achieves therapeutic concentrations only in urine. It is particularly active against Escherichia coli and some strains of Enterococcus, Klebsiella, and Staphylococcus. Due to its targeted spectrum and localized action, it is generally reserved for infections caused by susceptible organisms within the urinary tract, reducing the risk of systemic side effects. Nitrofurantoin's limited systemic absorption and rapid renal clearance contribute to its targeted action profile, making it a vital option in the specific context of urinary tract infections.Formula:C8H6N4O5Purezza:Min. 98 Area-%Colore e forma:Yellow PowderPeso molecolare:238.16 g/molNitrofurantoin
CAS:NitrofurantoinFormula:C8H6N4O5Purezza:By hplc: 99.1% by area (Typical Value in Batch COA)Colore e forma: yellow solidPeso molecolare:238.15704g/molNitrofurantoin
CAS:Nitrofurantoin, an antibiotic, targets bacteria for urinary infections by blocking DNA, RNA, and protein synthesis.Formula:C8H6N4O5Purezza:99.77%Colore e forma:Orange-Yellow Needles From Dil Acetic Acid 1992)Peso molecolare:238.16Nitrofurantoin
CAS:Formula:C8H6N4O5Purezza:>98.0%(T)(HPLC)Colore e forma:Light orange to Yellow to Green powder to crystalPeso molecolare:238.16Nitrofurantoin
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormula:C8H6N4O5Colore e forma:Yellow PowderPeso molecolare:238.16 g/mol1-(((5-Nitrofuran-2-yl)methylene)amino)imidazolidine-2,4-dione
CAS:Purezza:95.0%Colore e forma:SolidPeso molecolare:238.158996582031252,4-Imidazolidinedione, 1-[[(5-nitro-2-furanyl)methylene]amino]-
CAS:Formula:C8H6N4O5Purezza:%Colore e forma:SolidPeso molecolare:238.15704000000002Ref: 4Z-N-3412
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