![5,5′-Dithiobis[2-nitrobenzoic acid]](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fcas-image%2Fthumb-webp%2F169543-55-dithiobis-2-nitrobenzoic-acid.webp&w=3840&q=75)
CAS 69-78-3: Acido 5,5′-ditiobis[2-nitrobenzoico]
Descrizione:
Acido 5,5′-ditiobis[2-nitrobenzoico], comunemente noto come DTNB, è un composto chimico ampiamente utilizzato in biochimica e biologia molecolare. È caratterizzato dalla sua apparente cristallina gialla ed è solubile in acqua e solventi organici. Il DTNB funge da reagente per la rilevazione di gruppi tiolici in proteine e peptidi grazie alla sua capacità di formare un prodotto colorato in reazione con gruppi sulfidrilici liberi. Il composto presenta due moieties di acido 2-nitrobenzoico collegate da un legame disolfuro, responsabile della sua reattività. Il DTNB è spesso impiegato in saggi per quantificare la concentrazione proteica e per studiare la cinetica enzimatica che coinvolge substrati contenenti tiolo. Inoltre, ha applicazioni nel campo dello sviluppo di farmaci e della ricerca biochimica. Le considerazioni di sicurezza includono maneggiarlo con cura, poiché può essere dannoso se ingerito o inalato, e deve essere utilizzato un adeguato equipaggiamento di protezione personale. In generale, il DTNB è uno strumento prezioso nell'analisi e nella ricerca biochimica.
Formula:C14H8N2O8S2
InChI:InChI=1S/C14H8N2O8S2/c17-13(18)9-5-7(1-3-11(9)15(21)22)25-26-8-2-4-12(16(23)24)10(6-8)14(19)20/h1-6H,(H,17,18)(H,19,20)
InChI key:InChIKey=KIUMMUBSPKGMOY-UHFFFAOYSA-N
SMILES:C(O)(=O)C1=C(N(=O)=O)C=CC(SSC2=CC(C(O)=O)=C(N(=O)=O)C=C2)=C1
Sinonimi:- 2,2'-Dinitro-5,5'-dithiodibenzoic acid
- 3,3'-Disulfanediylbis(6-Nitrobenzoate)
- 3,3'-Disulfanediylbis(6-Nitrobenzoic Acid)
- 3,3'-Dithiobis(6-nitrobenzoic acid)
- 3,3'-Dithiobis[6-nitrobenzoe]saure
- 3-Carboxy-4-nitrophenyl disulfide
- 3-Carboxy-4-nitrophenyl disulphide
- 5,5-Dithio-Bis(2-Nitrobenzoic Acid)
- Acide 3,3'-dithiobis[6-nitrobenzoique]
- Acido 3,3'-Ditiobis[6-Nitrobenzoico]
- Ba 2767
- Vedi altri sinonimi
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12 prodotti.
5,5'-Dithiobis(2-nitrobenzoic acid)
CAS:5,5'-Dithiobis(2-nitrobenzoic acid)Formula:C14H8N2O8S2Purezza:By hplc: 98.29% (Typical Value in Batch COA)Colore e forma: yellow solidPeso molecolare:396.35g/mol3,3'-Dithiobis[6-nitrobenzoic Acid]
CAS:Applications 3,3'-Dithiobis[6-nitrobenzoic Acid is an membrane-impermeant thiol/disulfide exchange blocker. 3,3'-Dithiobis[6-nitrobenzoic Acid is also used to quantify the number or concentration of thiol groups in a sample. References Calderon, M.N., et al.: Intervirol., 55, 451 (2012); Li, J.M., et al.: J. Material. Chem., 22, 12100 (2012);Formula:C14H8N2O8S2Colore e forma:NeatPeso molecolare:396.355,5'-Dithiobis(2-nitrobenzoic acid)
CAS:DTNB is known as Ellman's reagent. It is used for the colorimetric determination of thiol groups in biological samples.It is fairly soluble in water. Colorless DTNB is converted to yellow 5-Mercapto-2-nitrobenzoic acid in the presence of thiol compounds. For example, DTNB in combination with S-acetylthiocholine iodide as the substrate is widely used to assay choline esterase activity.Formula:C14H8N2O8S2Purezza:Min. 98.0 Area-%Peso molecolare:396.36 g/mol5,5'-Dithiobis(2-nitrobenzoic acid), 99%
CAS:Reagent for determination of sufhydryl groups.5,5'-dithiobis-(2-nitrobenzoic acid) is widely utilized as a non-fluorescent probe to quantify the number or the concentration of thiol groups in a sample. It acts as a cleavable cross-linking agent. It finds an important application as a sensitive reagent for determining free sulfhydryl content in proteins, peptides, and tissues. It is also employed in high-performance liquid chromatography (HPLC) to determine the alkylthiol content. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Formula:C14H8N2O8S2Purezza:99%Colore e forma:Pale yellow to pale cream, PowderPeso molecolare:396.365,5''-Dithio-bis(2-nitrobenzoic acid)
CAS:Formula:C14H8N2O8S2Purezza:(HPLC) ≥ 98.5%Colore e forma:Off-white to yellow powder or crystalsPeso molecolare:396.365,5'-Dithiobis(2-nitrobenzoic Acid) [for Determination of SH groups]
CAS:Formula:C14H8N2O8S2Purezza:>98.0%(T)(HPLC)Colore e forma:Light yellow to Yellow powder to crystalPeso molecolare:396.34DTNB
CAS:DTNB, or Ellman's Reagent, quantifies thiol groups and measures low-mass thiols like glutathione in pure and biological samples.Formula:C14H8N2O8S2Purezza:97.91% - 99.51%Colore e forma:Yellow SolidPeso molecolare:396.35Benzoic acid, 3,3'-dithiobis[6-nitro-
CAS:Formula:C14H8N2O8S2Purezza:98%Colore e forma:SolidPeso molecolare:396.35191999999995,5'-Dithiobis(2-nitrobenzoic acid)
CAS:DTNB is known as Ellman's reagent. It is used for the colorimetric determination of thiol groups in biological samples.It is fairly soluble in water. Colorless DTNB is converted to yellow 5-Mercapto-2-nitrobenzoic acid in the presence of thiol compounds. For example, DTNB in combination with S-acetylthiocholine iodide as the substrate is widely used to assay choline esterase activity.Formula:C14H8N2O8S2Purezza:Min. 98 Area-%Colore e forma:Yellow PowderPeso molecolare:396.35 g/mol5,5'-Dithiobis-(2-nitrobenzoic acid), 99%
CAS:This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Purezza:99%Colore e forma:Crystalline powder, Off-white to yellow
![3,3'-Dithiobis[6-nitrobenzoic Acid]](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb%2FD479840.jpg&w=3840&q=75)
![5,5'-Dithiobis(2-nitrobenzoic Acid) [for Determination of SH groups]](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3B%2Fthumb%2FD0944.jpg&w=3840&q=75)
