CAS: 71222-06-5

Schizandriside shows anti-inflammatory properties, inhibits NO and PGE2, is cytotoxic to several cancer cells with IC50 of 3.26-8.89 uM.

Schizandriside is a bioactive lignan, which is a secondary metabolite primarily derived from the fruit of Schisandra chinensis, a plant native to East Asia. The compound is characterized by its exceptional antioxidant and adaptogenic properties, attributed to its intricate molecular structure that allows for free radical scavenging and stress response modulation. Schizandriside acts at a cellular level, enhancing the body's resilience to stress by modulating the hypothalamic-pituitary-adrenal axis. This alters cortisol levels and supports homeostasis during physiological challenges. Additionally, its antioxidant capabilities help reduce oxidative stress, a key factor in cellular aging and various pathological states. In scientific research, Schizandriside is employed extensively to explore its potential therapeutic applications. It has garnered interest for its role in neuroprotection, hepatic protection, and immune modulation. Ongoing studies aim to understand its efficacy and mechanisms in promoting cognitive function, mitigating liver damage, and enhancing immune response. This compound remains a pivotal subject in pharmacological studies due to its promising bioactivity and potential therapeutic benefits.