CAS: 73899-14-6

Applications A diazirine photophore used in photoaffinity labelling for probing receptor-ligand interfaces and other biopolymer research. References Hatanaka, Y. et al.: Heterocycles, 47, 625 (1998); Hashimoto, M. et al.: Anal. Biochem., 348, 154 (2006);

3-Phenyl-3-(trifluoromethyl)-3H-diazirine

3-Phenyl-3-(trifluoromethyl)diazirine is a molecule that has been studied extensively for its antimicrobial properties. It is effective against Gram-positive bacteria and some Gram-negative bacteria, but not against fungi or viruses. 3-Phenyl-3-(trifluoromethyl)diazirine binds to the active site of enzymes such as protein kinase C and phospholipase A2, inhibiting their activity. It also inhibits the growth of epidermal cells in culture by suppressing the production of epidermal growth factor (EGF). 3-Phenyl-3-(trifluoromethyl)diazirine has been shown to have an octameric structure, which may be important for its function.