CAS 951-78-0: Desossiuridina
Descrizione:
Desossiuridina è un nucleoside che gioca un ruolo cruciale nella sintesi del DNA. Consiste in una molecola di zucchero desossiribosio legata a una base di uracile, che è una delle quattro nucleobasi presenti nell'RNA, ma nel DNA è sostituita dalla timina. La formula chimica di Desossiuridina è C9H11N2O5, e ha un peso molecolare di circa 227,24 g/mol. Desossiuridina è tipicamente una polvere cristallina bianca a bianco sporco che è solubile in acqua e presenta un pH leggermente acido a neutro in soluzione. È coinvolto in vari processi biochimici, inclusa la replicazione e riparazione del DNA, e funge da substrato per l'enzima timidina chinasi, che lo fosforila per formare Desossiuridina trifosfato (dUTP). Questo composto è anche di interesse nella ricerca e nelle applicazioni terapeutiche, in particolare nello studio del metabolismo degli acidi nucleici e come potenziale agente antivirale. Il suo numero CAS è 951-78-0, che lo identifica in modo univoco nei database chimici.
Formula:C9H12N2O5
InChI:InChI=1S/C9H12N2O5/c12-4-6-5(13)3-8(16-6)11-2-1-7(14)10-9(11)15/h1-2,5-6,8,12-13H,3-4H2,(H,10,14,15)/t5-,6+,8+/m0/s1
InChI key:InChIKey=MXHRCPNRJAMMIM-SHYZEUOFSA-N
SMILES:O=C1N([C@@H]2O[C@H](CO)[C@@H](O)C2)C=CC(=O)N1
Sinonimi:- 1-(2-Deoxy-β-<span class="text-smallcaps">D</span>-erythro-pentofuranosyl)uracil
- 1-(2-Deoxy-β-D-erythro-pentofuranosyl)uracil
- 1-(2-deoxy-alpha-L-erythro-pentofuranosyl)pyrimidine-2,4(1H,3H)-dione
- 1-(2-deoxy-beta-L-erythro-pentofuranosyl)pyrimidine-2,4(1H,3H)-dione
- 1-(2-deoxypentofuranosyl)pyrimidine-2,4(1H,3H)-dione
- 1-[(3xi)-2-deoxy-beta-D-glycero-pentofuranosyl]pyrimidine-2,4(1H,3H)-dione
- 2'-Desoxiuridina
- 2'-Desoxyuridin
- 2'-Desoxyuridine
- 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-β-<span class="text-smallcaps">D</span>-erythro-pentofuranosyl)-
- 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-β-<span class="text-smallcaps">D</span>-ribofuranosyl)-
- Vedi altri sinonimi
Ordinare per
16 prodotti.
2'-Deoxyuridine
CAS:Please enquire for more information about 2'-Deoxyuridine including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C9H12N2O5Purezza:Min. 98 Area-%Peso molecolare:228.2 g/molRef: 3D-Q-200273
1kgPrezzo su richiesta100gPrezzo su richiesta250gPrezzo su richiesta500gPrezzo su richiesta2500gPrezzo su richiesta2'-Deoxyuridine
CAS:2'-DeoxyuridineFormula:C9H12N2O5Purezza:By hplc: 99.2% by area (230nm) (Typical Value in Batch COA)Colore e forma: white crystalline powderPeso molecolare:228.20g/mol1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
CAS:Formula:C9H12N2O5Purezza:98%Colore e forma:SolidPeso molecolare:228.2022'-Deoxyuridine
CAS:Formula:C9H12N2O5Purezza:>99.0%(HPLC)Colore e forma:White to Almost white powder to crystalPeso molecolare:228.202'-Deoxyuridine
CAS:2'-Deoxyuridine (2-deoxyuridine).Formula:C9H12N2O5Purezza:99.88% - 99.92%Colore e forma:SolidPeso molecolare:228.22''-Deoxyuridine
CAS:Formula:C9H12N2O5Purezza:≥ 99.0%Colore e forma:White to off-white crystalline powderPeso molecolare:228.212'-Deoxyuridine, 99+%
CAS:This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Formula:C9H12N2O5Purezza:99+%Colore e forma:White to off-white, PowderPeso molecolare:228.20Ref: ST-EA-CP-T185004
10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiesta1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
CAS:Purezza:97.0%Colore e forma:Solid, Crystalline PowderPeso molecolare:228.203994750976562'-Deoxyuridine-2-13C;1,3-15N
CAS:Purezza:99 atom % 13C; 99 atom % 15NColore e forma:White SolidPeso molecolare:231.232’-Deoxyuridine
CAS:Applications An uridine derivative as therapeutic agent for treating allergy, cancer, infection and autoimmune disease. References Fu, M., et al.: J. Biol. Chem., 271, 9982 (1996), Thornalley, P., et al.: Biochem. J., et al.: 344, 109 (1999), Munter, T., et al.: Chem. Res. Toxicol., 15, 1549 (2002)Formula:C9H12N2O5Colore e forma:NeatPeso molecolare:228.202'-Deoxyuridine
CAS:2'-Deoxyuridine (2'-dU) is an intermediate in the synthesis of thymidylate, which is a precursor for DNA synthesis. It can be prepared through high-performance liquid chromatography. 2'-dU has been shown to inhibit the enzymatic activity of enzymes responsible for synthesizing uridine and thymidylate, leading to neuronal death. 2'-dU has also been shown to have a protective effect against mitochondrial dysfunction induced by hydrogen fluoride. It is also known to bind with toll-like receptor 4 (TLR4), which is involved in inflammatory responses. 2'-dU has been used as a fluorescence probe for nucleic acids and as a polymerase chain reaction (PCR) substrate.Formula:C9H12N2O5Purezza:Min. 98 Area-%Colore e forma:White PowderPeso molecolare:228.21 g/mol2'-Deoxyuridine, 98+%
CAS:2'-Deoxyuridine is frequently halogenated to create thymidine analogues useful for studies of DNA synthesis and degradation mechanisms. Derivatized 2?-Deoxyuridines used as labeling substrates include chloro-2?-deoxyuridine (CldU), bromodeoxyuridine (BrdU) and/or iododeoxyuridine (IdU). Other useful analogues of 2?-deoxyuridine include 5-ethynyl-2?-deoxyuridine (DdU) and 5-hydroxymethyl-2?-deoxyuridine (HmdU). Laboratory suppression of deoxyuridine is used to diagnose megaloblastic anemias due to vitamin B12 and folate deficiencies. Deoxyuridine (dU) is used to indirectly determine if there are sufficient levels of folate and cobalamin in cell or tissue samples. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Formula:C9H12N2O5Purezza:98+%Colore e forma:Crystals or powder or crystalline powder, White to pale creamPeso molecolare:228.20
