CAS: 96614-01-6

cis-Isoadhumulone is an iso-alpha acid, a type of compound derived from the hops plant used in beer production. It is primarily obtained through the isomerization of humulone, a process that typically occurs during the brewing stage when hop resins are heated. The mode of action of cis-Isoadhumulone involves interacting with taste receptors to impart a distinctive bitterness. Additionally, it exhibits antimicrobial properties, particularly against gram-positive bacteria, due to its ability to disrupt bacterial cell membranes. The primary application of cis-Isoadhumulone lies in the brewing industry, where it serves as a crucial component in developing the desired flavor profile of beer by contributing to its bitterness. Beyond beer production, its antimicrobial properties have been explored in food preservation and safety, offering a natural alternative to synthetic preservatives. Research into its pharmacological potential is ongoing, including studies on anti-inflammatory and anticancer activities, though these uses remain experimental. The compound's dual role in flavoring and preservation highlights its significance in both culinary and scientific contexts.