CAS: 97399-70-7

Nortanshinone is a diterpene compound, which is a type of organic molecule composed of four isoprene units. It is derived from the roots of the plant Salvia miltiorrhiza, commonly known as Danshen, which is traditionally used in Chinese medicine. The mode of action of nortanshinone involves modulating various signaling pathways, including those associated with inflammation and apoptosis. It has been shown to inhibit the activity of nuclear factor-kappa B (NF-κB), a protein complex that plays a critical role in regulating immune response and cell survival. Its uses and applications are primarily in the realm of biomedical research. Nortanshinone is studied for its potential anti-inflammatory and anti-cancer properties. It has demonstrated the ability to reduce the proliferation of certain cancer cell lines and to mitigate inflammatory responses. This makes it a compound of interest in the development of new therapeutic strategies for diseases characterized by excessive inflammation or malignancy. Further elucidation of its mechanisms may support its inclusion in pharmacological studies and applications.

Nortanshinone is a natural product isolated from Dan-Shen.