Nrf2
Nrf2 è un fattore di trascrizione che regola l'espressione di proteine antiossidanti ed enzimi di detossificazione, svolgendo un ruolo fondamentale nella difesa cellulare contro lo stress ossidativo e l'infiammazione. L'attivazione della segnalazione Nrf2 fornisce protezione contro varie malattie, tra cui il cancro, la neurodegenerazione e i disturbi cardiovascolari. I modulatori di Nrf2 sono oggetto di studio per le loro potenziali applicazioni terapeutiche nella riduzione dei danni ossidativi e dell'infiammazione. Presso CymitQuimica, offriamo una gamma di modulatori della via Nrf2 di alta qualità per supportare la tua ricerca sullo stress ossidativo, l'infiammazione e la prevenzione delle malattie.
Prodotti di "Nrf2"
Ordinare per
NK-252
CAS:NK-252 is a potential activator of Nrf2. It has great Nrf2-activating potential.Formula:C13H11N5O3Purezza:98.32%Colore e forma:SolidPeso molecolare:285.26KI696
CAS:KI696 is a high-affinity probe that potently inhibits the interaction of Keap1 and NRF2.Formula:C28H30N4O6SPurezza:98.42%Colore e forma:SolidPeso molecolare:550.63Ref: TM-T11758L
1mg144,00€5mg350,00€10mg558,00€25mg1.026,00€50mg1.406,00€100mg1.872,00€1mL*10mM (DMSO)449,00€Anti-NFE2L2 Antibody (9K94)
Anti-NFE2L2 Antibody (9K94) is a Mouse antibody targeting NFE2L2. Anti-NFE2L2 Antibody (9K94) can be used in ELISA, WB, IHC, IF, FCM.Purezza:>95%Colore e forma:Odour LiquidML162
CAS:ML162 is a covalent glutathione peroxidase 4 (GPX4) inhibitor that induces ferroptosis. ML162 has antitumor activity. Cost-effective and quality-assured.Formula:C23H22Cl2N2O3SPurezza:98.42% - 99.78%Colore e forma:SolidPeso molecolare:477.4NSC23925
CAS:NSC23925 is a selective and effective inhibitor of P-glycoprotein (Pgp).Formula:C22H26Cl2N2O2Purezza:98%Colore e forma:SolidPeso molecolare:421.36Rehmapicrogenin
CAS:Rehmapicrogenin regulates the Nrf2/ARE signaling pathway. Nrf2/ARE signaling pathway is the most important pathway of oxidative stress.Formula:C10H16O3Purezza:98%Colore e forma:SolidPeso molecolare:184.23Kinsenoside
CAS:Kinsenoside ((+)-Kinsenoside) shows significant antihepatotoxic, and anti-inflammatory activities.Formula:C10H16O8Purezza:100% - 99.92%Colore e forma:SolidPeso molecolare:264.23VVD-130037
CAS:VVD-130037 is a KEAP1 activator with potential antitumor activity.VVD-130037 inhibits tumor growth in advanced solid tumors by degrading NRF2.Formula:C17H17ClN4O2Purezza:99.01%Colore e forma:SolidPeso molecolare:344.8CDDO-EA
CAS:CDDO-EA (CDDO ethyl amide) is an activator of the Nrf2/antioxidant response element.Formula:C33H46N2O3Purezza:98.54%Colore e forma:SolidPeso molecolare:518.73Ref: TM-T10733
1mg85,00€5mg169,00€10mg298,00€25mg512,00€50mg732,00€100mg944,00€200mg1.264,00€1mL*10mM (DMSO)187,00€Ezetimibe
CAS:Ezetimibe (SCH 58235) is a Dietary Cholesterol Absorption Inhibitor. The physiologic effect of ezetimibe is by means of Decreased Cholesterol Absorption.Formula:C24H21F2NO3Purezza:97.28% - 99.97%Colore e forma:SolidPeso molecolare:409.43Ref: TM-T1593
1g283,00€10mg48,00€25mg62,00€50mg77,00€100mg87,00€200mg125,00€500mg197,00€1mL*10mM (DMSO)55,00€(E/Z)-BCI
CAS:(E/Z)-BCI (NSC-150117), a dual-specificity phosphatase 6 (DUSP6) inhibitor with anti-inflammatory properties, reduces LPS-induced inflammatory mediators and ROSFormula:C22H23NOPurezza:98.55%Colore e forma:SolidPeso molecolare:317.42Ref: TM-T11139
1mg80,00€5mg155,00€10mg283,00€25mg452,00€50mg638,00€100mg848,00€200mg1.121,00€1mL*10mM (DMSO)170,00€4-Octyl itaconate
CAS:4-Octyl Itaconate is a cell-permeable derivative of Itaconate, an anti-inflammatory metabolite.Formula:C13H22O4Purezza:99.3% - 99.94%Colore e forma:SolidPeso molecolare:242.31CPUY192018
CAS:CPUY192018 is an inhibitor of Keap1-Nrf2 protein-protein interactions, and can be used to study mitochondrial autophagy.Formula:C28H26N2O10S2Purezza:98.9%Colore e forma:SolidPeso molecolare:614.64TAT 14
CAS:TAT 14: a 14-mer peptide Nrf2 activator, anti-inflammatory, boosts Nrf2 protein, targets Keap1, no effect on mRNA.Formula:C137H230N48O39Purezza:98%Colore e forma:SolidPeso molecolare:3173.59ML334
CAS:ML334 (LH601A) is an NRF2 activator that inhibits cardiac fibroblast activation and proliferation ameliorating myocardial infarction-induced cardiac fibrosis.Formula:C26H26N2O5Purezza:98.06% - 98.06%Colore e forma:SolidPeso molecolare:446.49CBR-470-1
CAS:CBR-470-1 is a glycolytic phosphoglycerate kinase 1 inhibitor and Nrf2 activator that exhibits neuroprotective activity by activating the Keap1-Nrf2 cascade.Formula:C14H20ClNO4S2Purezza:98.03%Colore e forma:SolidPeso molecolare:365.9RA-839
CAS:RA-839 is a Keap1 conjugate and Nrf2 signaling activator, and an inhibitor of Keap1/Nrf2 interaction with anticancer activity.Formula:C25H28N2O4SPurezza:98.38%Colore e forma:SolidPeso molecolare:452.57Gingerenone A
CAS:Gingerenone A, an Nrf2-Gpx4 activator isolated from ginger, has anticancer activity and inhibits iron death in mice with colitis secondary to liver injury (SLI)Formula:C21H24O5Purezza:98.94%Colore e forma:SolidPeso molecolare:356.41Nrf2 activator-1
CAS:Nrf2 activator-1 activates Nrf2; used for COPD, asthma, ALI, ARDS, pulmonary fibrosis research.Formula:C30H34N4O6SPurezza:≥98%Colore e forma:SolidPeso molecolare:578.68KI696 isomer
CAS:KI696 isomer is an isomer of KI696, a low affinity probe for the study of immune and metabolic diseases.Formula:C28H30N4O6SPurezza:99.8%Colore e forma:SolidPeso molecolare:550.63Ref: TM-T11758
1mg154,00€5mg464,00€10mg777,00€25mg1.568,00€50mg2.110,00€100mg2.783,00€1mL*10mM (DMSO)510,00€
