
Cellule staminali e Derivati
Gli inibitori delle cellule staminali sono composti che bersagliano specificamente le vie di segnalazione e le proteine coinvolte nel mantenimento, nella differenziazione e nella proliferazione delle cellule staminali. Questi inibitori sono cruciali per comprendere la biologia delle cellule staminali e per sviluppare strategie per manipolare le cellule staminali a fini terapeutici, come la medicina rigenerativa e il trattamento del cancro. Controllando il destino delle cellule staminali, questi inibitori possono aiutare a guidare la differenziazione delle cellule staminali in tipi cellulari specifici o a prevenire una crescita cellulare indesiderata. Presso CymitQuimica, offriamo una selezione di inibitori delle cellule staminali di alta qualità per supportare la tua ricerca in biologia delle cellule staminali, biologia dello sviluppo e medicina rigenerativa.
Sottocategorie di "Cellule staminali e Derivati"
- Gamma-secretasi
- Proteina Hedgehog/Smoothened
- Via di segnalazione Hippo
- JAK
- Proteina Porcupine
- ROCK
- STAT
- Cellule staminali
- TGF-beta/Smad
- Wnt/beta-catenina
Mostrare 2 più sottocategorie
Prodotti di "Cellule staminali e Derivati"
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IWP L6
CAS:IWP L6 (Porcn Inhibitor III) is an extremely effective Porcn inhibitor (EC50: 0.5 nM).Formula:C25H20N4O2S2Purezza:100% - 99.74%Colore e forma:SolidPeso molecolare:472.58AJI-214
CAS:AJI-214 functions as a dual-target inhibitor that specifically blocks Aurora kinase A and JAK2. By directly inhibiting Aurora kinase A, AJI-214 prevents mitotic progression and cell polarity in T cells while concurrently suppressing JAK2 activation to reduce STAT3 phosphorylation. This inhibition decreases the differentiation of TH1 and TH17 cells. AJI-214 is utilized in research focused on the modulation of immune responses and the prevention of graft-versus-host disease (GVHD).Formula:C17H13ClFN5OColore e forma:SolidPeso molecolare:357.77YAP/TAZ inhibitor-4
YAP/TAZ Inhibitor-4 (Compound 45) acts as an inhibitor of YAP/TAZ, exhibiting inhibitory activity on TEAD transcriptional activation by preventing the interaction between YAP or TAZ and TEAD.Formula:C28H28F3N3O3Colore e forma:SolidPeso molecolare:511.54Casein kinase 1δ-IN-8
CAS:Casein kinase 1δ-IN-8 is an inhibitor of casein kinase 1δ and is used to treat neurodegenerative diseases such as Alzheimer's disease type.Formula:C19H14FN5OSPurezza:99.66%Colore e forma:SolidPeso molecolare:379.41NMS-P715
CAS:NMS-P715 is a highly selective and ATP-competitive MPS1 inhibitor(IC50 of 182 nM).Formula:C35H39F3N8O3Purezza:98.41%Colore e forma:SolidPeso molecolare:676.73Cucurbitacin A
CAS:Cucurbitacin I, cytotoxic triterpenoid sterols isolated from plants, elicits the formation of actin/phospho-myosin II co-aggregates by stimulation of the RhoA/Formula:C32H46O9Purezza:98%Colore e forma:SolidPeso molecolare:574.7Ifidancitinib
CAS:Ifidancitinib (ATI-50002) is a JAK kinase 1/3 inhibitor used to study autoimmune diseases.Formula:C20H18FN5O3Purezza:98.05%Colore e forma:SolidPeso molecolare:395.39Anti-5T4/TPBG Antibody (9P872)
Anti-5T4/TPBG Antibody (9P872) is an antibody targeting 5T4/TPBG. Anti-5T4/TPBG Antibody (9P872) can be used in ELISA, FCM.Colore e forma:Odour LiquidJAK-IN-10
CAS:JAK-IN-10 is a JAK inhibitor. JAK-IN-10 can be used for the research of dry eye disorders.Formula:C20H18FN5O3SPurezza:98.88%Colore e forma:SolidPeso molecolare:427.45Ref: TM-T13571
1mg87,00€5mg177,00€10mg260,00€25mg429,00€50mg605,00€100mg815,00€500mg1.624,00€1mL*10mM (DMSO)188,00€WDR5-IN-6
CAS:WDR5-IN-6 is a WDR5 inhibitor targeting the WBM locus.WDR5-IN-6 is highly synergistic with OICR-9429, a WDR5 inhibitor that targets the WIN locus.WDR5-IN-6Formula:C13H8Cl2N2O2SPurezza:99.69%Colore e forma:SoildPeso molecolare:327.19JAK kinase-IN-1
CAS:JAK kinase-IN-1 (Example 1) functions as a potent inhibitor targeting the JAK family, which includes TYK2, JAK1, JAK2, and JAK3, with IC50 values of 4.2 nM, 32Formula:C17H19F2N7OSPurezza:98%Colore e forma:SolidPeso molecolare:407.44ITK inhibitor 2
CAS:ITK inhibitor 2 is a interleukin-2-inducible T-cell kinase (ITK) inhibitor , with an IC50 of 2 nM.Formula:C25H33N5O2Colore e forma:SolidPeso molecolare:435.56STAT6-IN-3
CAS:STAT6-IN-3 (Compound 18a) serves as an inhibitor of STAT6 with an IC50 value of 44 nM, specifically targeting the Src Homology 2 (SH2) domain.Formula:C32H35IN3O7PPurezza:98%Colore e forma:SolidPeso molecolare:731.51CCG-232964
CAS:CCG-232964 is an orally active Rho/MRTF/SRF inhibitor that suppresses LPA-induced CTGF gene expression [1].Formula:C15H15ClN2O3SPurezza:98%Colore e forma:SolidPeso molecolare:338.81LX7101
CAS:LX7101 is an effective inhibitor of LIMK and ROCK2 (IC50: 24, 1.6, and 10 nM for LIMK1, LIMK2, and ROCK2, respectively). It also inhibits PKA (IC50 <1 nM).Formula:C23H29N7O3Purezza:98.42%Colore e forma:SolidPeso molecolare:451.52Dehydroglyasperin D
CAS:Dehydroglyasperin D exhibits anticancer, anti-inflammatory, anti-obesity, antioxidant and anti-aldose reductase effects, it inhibits the proliferation of HT-29Formula:C22H24O5Purezza:98%Colore e forma:SolidPeso molecolare:368.42SR-3677
CAS:SR-3677 is an effective and specific inhibitor of ROCK2 (IC50: 3 nM).Formula:C22H24N4O4Purezza:98.46%Colore e forma:SolidPeso molecolare:408.45ZINC00881524
CAS:ZINC00881524 (ROCK inhibitor) is an effective and specific ROCK inhibitor.Formula:C21H20N2O3SPurezza:99.48%Colore e forma:SolidPeso molecolare:380.46ROCK-IN-5
CAS:ROCK-IN-5 (I-B-37) inhibits kinases like ROCK/ERK/GSK; may aid in cardiac and neuro disease studies.Formula:C16H11ClFN3OSPurezza:99.03% - 99.69%Colore e forma:SolidPeso molecolare:347.79Ref: TM-T67748
10mg46,00€25mg69,00€50mg89,00€100mg135,00€500mgPrezzo su richiesta1mL*10mM (DMSO)35,00€Stafia-1
CAS:Stafia-1 is a potent STAT5a inhibitor ( IC50=22.2 μM). Stafia-1 displays high selectivity over STAT5b and other STAT family members.Formula:C24H27O10PPurezza:98.08%Colore e forma:SolidPeso molecolare:506.44Ref: TM-T9339
1mg86,00€5mg187,00€10mg309,00€25mg525,00€50mg757,00€100mg1.035,00€500mg2.110,00€1mL*10mM (DMSO)217,00€