Building Blocks

2-(4-Nitrophenyl)acetamide is an activating mutant of the enzyme phospholipase A2. It has been shown to selectively hydrolyze the fatty acid ester bond of phospholipids, which is required for cell membrane integrity. 2-(4-Nitrophenyl)acetamide is a molecule that binds to the active site of the enzyme and is stabilized by hydrogen bonding and van der Waals forces. 2-(4-Nitrophenyl)acetamide has been shown to be specific for phosphatidylethanolamine, which makes it a useful tool in studying the role of this lipid in cell signaling processes.

Versatile small molecule scaffold

(1S)-1-(Adamantan-1-yl)ethan-1-amine hydrochloride is a neuraminidase inhibitor that prevents the spread of influenza virus by inactivating its neuraminidase enzyme. It is used to treat or prevent influenza caused by either type A or B viruses, including swine flu. The drug is administered orally and has few side effects, although it can cause psychiatric disorders such as anxiety, agitation, or hallucinations.

1-(5-chloro-4-nitrothiophen-2-yl)ethan-1-one is a thiophene that has shown to have pharmacological activity in animal models. It has been shown to be a bifunctional compound, with the ability to serve as an amine and an alcohol. This functional group makes 1-(5-chloro-4-nitrothiophen-2-yl)ethan-1-one useful in the synthesis of benzodiazepines, which are important drugs for the treatment of anxiety.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

3-Isopropylbenzaldehyde is a flavonoid that has been shown to possess anti-inflammatory properties. It binds to the P38 and JNK pathways, which are associated with inflammation, in an animal model and inhibits the production of prostaglandin E2 by inhibiting the enzyme cyclooxygenase 2. 3-Isopropylbenzaldehyde also has been shown to inhibit fatty acid biosynthesis, which may be a strategy for treating obesity.

Versatile small molecule scaffold

Methyl 1,2,4-triazole-3-carboxylate

2-(Pyridin-3-yl)acetaldehyde

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

5-Amino-1-phenyl-1H-pyrazole-4-carbonitrile

7-Chloroisatin

3-Allyldihydro-2,5-furandione is a compound with a carbonyl group. It has been shown to be biocompatible and chemically stable in the presence of air and water. The chemical stability of the 3-allyldihydro-2,5-furandione is dependent on the linkage between its carbonyl group and the rest of its molecular structure. The ester linkages are more stable than ether or hydroxyl linkages. This compound has been shown to be an excellent candidate for use as a solvent in detergent compositions. 3-Allyldihydro-2,5-furandione can be synthesized by reacting phenol with 2,5-dihydroxybenzaldehyde and furan in an air entrainment reaction at an activation energy of 75 kJ/mol.

2-Amino-3,6-dimethylbenzoic acid is an equilibrating agent that has been used to study the interaction and kinetics of hydrogen bonds. It is a white crystalline solid with a molecular weight of 164.2 g/mol and a melting point of 127 °C. The kinetic method has been used to study the equilibration between its two forms: 3,4-dihydroxybenzoic acid (DHB) and 2-hydroxybenzoic acid (HBA). This equilibrium can be described by the equation DHB + HBA ⇌ DHB + HBA, where the equilibrium constant is K = [DHB][HBA]/[DHB][HBA]. The kinetic method was also applied to study the reaction between 2-amino-3,6-dimethylbenzoic acid and methyl derivatives of olefins. In this case, the kinetic method was used to determine

2-Chloromethyl-1,3-dioxolane

CRT0066854 is a small molecule that inhibits the activity of two protein kinases, p38 and JNK. This inhibitor binds to the ATP-binding site of these kinases, blocking ATP binding and subsequently inhibiting the phosphorylation of downstream proteins. CRT0066854 has been shown to inhibit TNF-α release in vitro and in vivo in mice with colitis. This drug also has anti-inflammatory effects in other models of bowel disease. CRT0066854 was found to inhibit the growth of colon cancer cells by preventing cell cycle progression at G2/M phase. This compound also inhibits the growth of breast cancer cells by promoting apoptosis through activation of caspase 3. CRT0066854 is an acidic compound with a molecular weight of 184.18 g/mol and a melting point of 68°C. It binds to two different protein kinases (p38 and JNK) that are involved in inflammatory responses and tumorigenesis.

Please enquire for more information about 4-Bromo-3-(trifluoromethoxy)pyridine hydrobromide including the price, delivery time and more detailed product information at the technical inquiry form on this page

Ethyl 1-(tert-butyl)-4,5-dioxopyrrolidine-3-carboxylate

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Diethyl {[(tetrahydro-2H-pyran-2-yl)oxy]methyl}phosphonate

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

2-Methyl-4-piperidinone hydrochloride

Versatile small molecule scaffold

2-(1,1-Dioxidothiomorpholin-4-yl)-3,3-dimethylbutanoic acid

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

4,5-Dichloroperfluoro(2,2-dimethyl-1,3-dioxolane)

Versatile small molecule scaffold

2,3-Dichloro-6-methoxypyridine

5-Bromo-6-fluoroquinoxaline

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Methyl 5-chloro-3-(chlorosulfonyl)thiophene-2-carboxylate is an industrial chemical that is used to produce other chemicals. Methyl 5-chloro-3-(chlorosulfonyl)thiophene-2-carboxylate is synthesized from the condensation of sarcosine and 2-aminopyridine with sodium methoxide in methanol. The reaction produces a methyl ester hydrochloride, which is subsequently converted into a methoxide by reacting with potassium hydroxide. Methyl 5-chloro-3-(chlorosulfonyl)thiophene-2-carboxylate has low toxicity and can be easily eliminated through the body's natural processes. It also has industrial applications, such as being used as a component in pesticides, herbicides, and insecticides.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Please enquire for more information about 2,6-Diaminotoluene including the price, delivery time and more detailed product information at the technical inquiry form on this page

Versatile small molecule scaffold

Please enquire for more information about 3-Fluoro-5-methoxybenzylamine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Versatile small molecule scaffold

5-Fluoro-1-(piperazin-1-yl)isoquinoline

2-Amino-5-[(4-ethyl-1-piperazinyl)methyl]pyridine

Versatile small molecule scaffold

5-Bromo-6-fluoropyridine-3-carbonitrile

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Applications Potassium Octadecanoate-2,2-d2 (CAS# 352438-86-9) is a useful isotopically labeled research compound.

Versatile small molecule scaffold

Versatile small molecule scaffold

1-(3-Chloro-2-methylphenyl)-1H-pyrrole

Versatile small molecule scaffold

Versatile small molecule scaffold

5,7-Bis(trifluoromethyl)-4-hydroxyquinoline

Versatile small molecule scaffold

4-Fluoro-5-iodo-1H-indazole

Versatile small molecule scaffold

2-(7-Oxo-5,8-diazaspiro[3.4]oct-6-yl)benzoic acid

L-Mimosine is a polymerase chain inhibitor that binds to the β subunit of RNA polymerase and inhibits transcription. The L-mimosine has been found to have significant cytotoxicity in human osteosarcoma cells and skin cancer cells. L-Mimosine has also been shown to inhibit tumor progression in vivo. In addition, L-mimosine has been shown to significantly increase the expression of dopamine β hydroxylase, an enzyme that converts dopamine into norepinephrine, which is important for healthy skin function. The kinetic data of L-mimosine was determined by measuring the inhibition of DNA synthesis following drug treatment. This data is represented as a percentage of control values and plotted against time.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

5-Chloro-6-nitro-1,3-benzoxazole

2,6-Dimethoxy-4-propylphenol is an organic solvent that is used in the synthesis of pharmaceuticals and agricultural chemicals. It is also a precursor for lignin, a natural polymer found in plants. 2,6-Dimethoxy-4-propylphenol can be converted to 2,6-dimethoxyphenol by hydrolysis with water vapor or an acid catalyst. The skeleton of 2,6-dimethoxy-4-propylphenol is a carbon chain with ether linkages that are susceptible to hydrolysis reactions. These reactions produce monomers and fatty acids.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold