![1,3-Dihydro-1-[2-hydroxy-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-2H-benzimidazol-2-one](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FFD172815.webp&w=3840&q=75)
1,3-Dihydro-1-[2-hydroxy-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-2H-benzimidazol-2-one
CAS:
Rif. 3D-FD172815
Informazioni sul prodotto
Nome:1,3-Dihydro-1-[2-hydroxy-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-2H-benzimidazol-2-one
Marchio:Biosynth
Descrizione:1,3-Dihydro-1-[2-hydroxy-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-2H-benzimidazol-2-one is a compound that inhibits mitochondrial respiratory complex I. It binds to the mitochondrial ATP synthase and prevents the synthesis of adenosine triphosphate (ATP), which is essential for the function of the mitochondria. This drug has been shown to inhibit microglia, which are cells in the central nervous system that play a role in inflammatory response. The drug also has been shown to induce reactive oxygen species production, as well as mitochondrial membrane depolarization and hyperpolarization in SKN-SH cells.
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Proprietà chimiche
Peso molecolare:362.23 g/mol
Formula:C15H8F6N2O2
Purezza:Min. 95%
InChI:InChI=1S/C15H8F6N2O2/c16-14(17,18)7-1-3-10-9(5-7)22-13(25)23(10)11-6-8(15(19,20)21)2-4-12(11)24/h1-6,24H,(H,22,25)
InChI key:InChIKey=YLFMCMWKHSDUCT-UHFFFAOYSA-N
SMILES:O=c1[nH]c2cc(C(F)(F)F)ccc2n1-c1cc(C(F)(F)F)ccc1O