4-(1-Methyl-piperidin-4-yl)aniline
CAS:
Rif. 3D-FM51997
Informazioni sul prodotto
Nome:4-(1-Methyl-piperidin-4-yl)aniline
Marchio:Biosynth
Descrizione:4-(1-Methyl-piperidin-4-yl)aniline (4MPaA) is a small molecule that has been shown to inhibit the kinase activity of PIM-1, which is a tyrosine kinase that is associated with chronic myeloid leukemia. In vitro studies have shown that 4MPaA inhibits the proliferation of human chronic myeloid leukemia cells, and also reduces their viability. This compound also inhibits murine leukemia in vivo, and has been shown to be selective for inhibiting the growth of murine cells over human cells in vitro. 4MPaA is an example of a novel class of compounds that inhibit PIM-1 by targeting its ATP binding site.
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Proprietà chimiche
Peso molecolare:190.28 g/mol
Formula:C12H18N2
Purezza:Min. 95%
InChI:InChI=1S/C12H18N2/c1-14-8-6-11(7-9-14)10-2-4-12(13)5-3-10/h2-5,11H,6-9,13H2,1H3
InChI key:InChIKey=BNYVBWBKNDWCQW-UHFFFAOYSA-N
SMILES:CN1CCC(c2ccc(N)cc2)CC1