Product Information
Name:Fmoc-Glu(2-phenylisopropyl ester)-OH
Synonyms:
- Fmoc-Glu(OPp)-OH
Brand:Bachem
Description:Glu-derivative for the selective modification of the γ-carboxyl group. The OPp group can be removed selectively in the presence of Boc/OtBu with 1% TFA/DCM. Ocampo et al. applied OPp protection during the synthesis of a peptide-oligonucleotide conjugate and cleaved it with 3% trichloroacetic acid in DCM. Tofteng et al. generated a backbone pyroglutamyl imide moiety from C-terminal Glu after selective on-resin OPp removal.
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Chemical properties
Molecular weight:487.55
Formula:C29H29NO6
Purity:99.38%
Color/Form:White Powder
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