L-trans-Epoxysuccinyl-Leu-3-methylbutylamide-ethyl ester
CAS:
Ref. 01-4027911
1mg
166.00€
5mg
642.00€
Product Information
Name:L-trans-Epoxysuccinyl-Leu-3-methylbutylamide-ethyl ester
Synonyms:
- L-trans-Epoxysuccinyl(OEt)-Leu-3-methylbutylamide
Brand:Bachem
Description:E64d (EST), a membrane permeable analog of E64c, was expected to be useful as an oral drug for muscular dystrophy due to its potent inhibitory activities against the cysteine proteinases involved in the myofibrillar protein degradation that occurs in this disease. E64d attenuates the effects of parathyroid hormone on osteoblasts in vitro. By inhibiting cathepsin B, a cysteine protease showing β-secretase activity, E64d could reduce brain Aβ and improve memory deficits in Alzheimer’s disease animal models.
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Chemical properties
Molecular weight:342.44
Formula:C17H30N2O5
Purity:> 99%
Color/Form:White
Technical inquiry about: L-trans-Epoxysuccinyl-Leu-3-methylbutylamide-ethyl ester
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