Product Information
Name:11-Dehydrocorticosterone-13C3
Controlled Product
Brand:Biosynth
Description:11-Dehydrocorticosterone-13C3 is a synthetic glucocorticoid that is used as a nasal drug. It has been shown to inhibit the production of inflammatory cytokines, such as tumor necrosis factor and interleukin-1β, which are involved in the pathogenesis of autoimmune diseases. 11-Dehydrocorticosterone-13C3 binds to the glucocorticoid receptor with high affinity and specificity and possesses a hydroxyl group at C3 position. It is effective in inhibiting the production of proinflammatory cytokines in 3T3-L1 preadipocytes by blocking the function of nuclear factor kappa B (NFκB). It also inhibits the release of colony stimulating factors, such as granulocyte macrophage colony stimulating factor (GMCSF) and granulocyte colony stimulating factor (GCSF), from 3t3-l1 preadipocytes.
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Chemical properties
Molecular weight:347.42 g/mol
Formula:C21H28O4
Purity:Min. 95%
Technical inquiry about: 11-Dehydrocorticosterone-13C3
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