Product Information
Name:2'-Deoxycoformycin
Synonyms:
- pentostatin
Brand:Biosynth
Description:2'-Deoxycoformycin is a potent adenosine deaminase inhibitor, which is derived from the fermentation of Streptomyces antibioticus, a species of actinomycete bacteria. This compound acts by specifically inhibiting the enzyme adenosine deaminase, leading to an accumulation of toxic deoxyadenosine triphosphate in lymphocytes. This buildup hinders DNA synthesis, effectively suppressing the proliferation of lymphoid cells.
In clinical settings, 2'-Deoxycoformycin, also known as pentostatin, is used primarily in the treatment of certain types of cancer, such as hairy cell leukemia and chronic lymphocytic leukemia. Its mode of action makes it highly effective as a chemotherapeutic agent, particularly due to its ability to induce apoptosis in malignant cells. Researchers are also exploring its potential in treating autoimmune disorders, taking advantage of its immune-modulating properties. The specificity of 2'-Deoxycoformycin for adenosine deaminase makes it a valuable tool in both therapeutic applications and scientific research, highlighting its significance in biochemical studies and drug development.
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Chemical properties
Molecular weight:268.27 g/mol
Formula:C11H16N4O4
Purity:Min. 95%
Technical inquiry about: 2'-Deoxycoformycin
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