Product Information
Name:Gliotoxin
Brand:Biosynth
Description:Gliotoxin is a bioactive mycotoxin and antibiotic compound, which is primarily derived from various species of Aspergillus and Penicillium fungi. This epipolythiodioxopiperazine (ETP) toxin possesses a unique disulfide bridge that plays a pivotal role in its biological activity. Gliotoxin exerts its effects through the induction of oxidative stress by generating reactive oxygen species (ROS) and disrupting cellular redox balance. Additionally, it can inhibit the activation of crucial transcription factors like NF-κB, thereby modulating immune responses.
In scientific research, gliotoxin is extensively used to study fungal pathogenicity, particularly in Aspergillus fumigatus, a significant opportunistic pathogen. Its immunosuppressive properties make it a valuable tool for exploring immune system dynamics, especially in the context of transplantation and autoimmune diseases. However, due to its potent cytotoxicity, caution is warranted in handling this compound, emphasizing controlled experimental settings to unravel its complex biological roles.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:326.0395
Formula:C13H14N2O4S2
Purity:Min. 95%
Technical inquiry about: Gliotoxin
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