

APcK 110
CAS:
Ref. 3D-BQB08374


Product Information
Name:APcK 110
Brand:Biosynth
Description:APCK-110 is a tyrosine kinase inhibitor that has been shown to inhibit the constitutive activation of the mastocytosis receptor tyrosine kinase, KIT. APCK-110 has also demonstrated efficacy in clinical studies involving patients with leukemia who were resistant to imatinib and dasatinib. The drug inhibits proliferation of cancer cells, and may also be able to differentiate between leukemias and stem cells. The drug has been shown to have toxicities, such as anemia, neutropenia, thrombocytopenia, and hepatotoxicity. These toxicities are dose-dependent, with the most severe side effects seen at high doses.
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Chemical properties
Molecular weight:349.4 g/mol
Formula:C20H16FN3O2
Purity:Min. 95%