

SARS-CoV-2 main protease
CAS:
Ref. 3D-BS178678
1mg
918.00€
2mg
1,655.00€
5mg
3,778.00€
10mg
6,991.00€


Product Information
Name:SARS-CoV-2 main protease
Brand:Biosynth
Description:The main protease Mpro is a key protein in the lifecycle of the SARS-CoV-2 virus. Mpro cleaves the viral polyproteins at the C-terminal end of a glutamine residue in recognition sequences containing Leu-Gln-(Ser, Ala, Gly) motifs (Rut et al, 2020). As SARS-CoV-2 MPro has no closely related homologues in humans, it represents an attractive drug target (Ullrich and Nitsche, 2020). In summary, the Mpro protease is a chymotrypsin-like cysteine protease, requires homodimerisation for proteolytic activity, cleaves the viral polyproteins in 11 distinct sites, exclusively after a glutamine residue. A fluorogenic substrate for Mpro assays is Ac-Abu-Tle-Leu-Gln-AMC.The protein amount or better its concentration in solution is quantified using either A280 (absorption at 280 nm with its specific absorption coefficient) or using the Bradford assay (uses the dye Coomassie Brilliant Blue). Both of these methods quantify the total amount of protein in a sample, no matter what the oligomerization state is.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Purity:(Sds-Page) Min. 80%
Color/Form:Lyophilisate
Technical inquiry about: SARS-CoV-2 main protease
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