Lipid A (E. coli)
Ref. 3D-CLP-24005-S
100µg
731.00€
Product Information
Name:Lipid A (E. coli)
Brand:Biosynth
Description:Lipid A is a component of the outer membrane of Gram-negative bacteria. Lipid A is a complex molecule that is composed of three major domains: an amino-terminal domain, a lipid tail, and a carboxy-terminal domain. The amino-terminal domain contains two receptor binding sites that are responsible for activating the innate immune system. Peptides in the amino-terminal domain bind to Toll-like receptor 4 (TLR4) and activate macrophages, which release inflammatory cytokines and nitric oxide. The lipid tail interacts with CD14 on macrophages, which leads to the activation of nuclear factor κB (NFκB). Activation of TLR4 and CD14 causes an increase in the production of proinflammatory cytokines. The carboxy-terminal domain binds to lipopolysaccharide (LPS) and prevents LPS from interacting with TLR4. The purified Lipid A is free from other
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:1,798.4 g/mol
Formula:C94H178N2O25P2
Purity:Min. 95%
Technical inquiry about: Lipid A (E. coli)
Please use instead the cart to request a quotation or an order
If you want to request a quotation or place an order, please instead add the desired products to your cart and then request a quotation or order from the cart. It is faster, cheaper, and you will be able to benefit from the available discounts and other advantages.