Acetyl-TGF-beta 2-LAPbeta (259- 269)
Ref. 3D-CRB1000322
1mg
265.00€
500µg
194.00€
Product Information
Name:Acetyl-TGF-beta 2-LAPbeta (259- 269)
Synonyms:
- Ac-YTSGDQKTIKS-NH2
Brand:Biosynth
Description:Latent TGF-β is a non-lysosomal glycoprotein with mannose 6-phosphate (Man-6-P) residues on its N-glycans. When it is released, latent TGF-β is bound to its latency-associated peptide (LAP), it must then be activated and released from LAP before it can bind to its cell surface-localised Man-6-P receptors and exert its biological activity. Activation can occur by various mechanisms in vivo, including those governed by integrins and thrombospondin. Mannose phosphorylation has also been implicated in this activation process. Man-6-P has been proposed as an anti-scarring therapy due to its ability to directly block the activation of latent TGF-β.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:1,267.6 g/mol
Color/Form:Powder
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